Extraction, purification, structure characteristics, biological activities and pharmaceutical application of Bupleuri radix polysaccharide: a review
X Yu, Z Miao, L Zhang, L Zhu, H Sheng - International Journal of Biological …, 2023 - Elsevier
Bupleuri Radix (BR), as a well-known plant medicine of relieving exterior syndrome, has a
long history of usage in China. Bupleuri Radix Polysaccharide (BRP), as the main …
long history of usage in China. Bupleuri Radix Polysaccharide (BRP), as the main …
[HTML][HTML] Potential herb‒drug interactions between anti-COVID-19 drugs and traditional Chinese medicine
L Ye, S Fan, P Zhao, C Wu, M Liu, S Hu, P Wang… - … Pharmaceutica Sinica B, 2023 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …
syndrome coronavirus 2 (SARS-CoV-2), has spread worldwide. Effective treatments against …
Herb–drug interactions of commonly used Chinese medicinal herbs
A Singh, K Zhao - International Review of Neurobiology, 2017 - Elsevier
With more and more popular use of traditional herbal medicines, in particular Chinese
herbal medicines, herb–drug interactions have become a more and more important safety …
herbal medicines, herb–drug interactions have become a more and more important safety …
Pharmacokinetic herb–drug interactions with traditional Chinese medicine: progress, causes of conflicting results and suggestions for future research
BL Ma, YM Ma - Drug metabolism reviews, 2016 - Taylor & Francis
Traditional Chinese medicine (TCM) has a long history of medical use in China and is still
used worldwide. Unexpected herb–drug interactions (HDIs) may lead to adverse drug …
used worldwide. Unexpected herb–drug interactions (HDIs) may lead to adverse drug …
Investigation of CYP2B6, 3A4 and β-esterase interactions of Withania somnifera (L.) dunal in human liver microsomes and HepG2 cells
S Kumar, PJ Bouic, B Rosenkranz - Journal of ethnopharmacology, 2021 - Elsevier
Ethnopharmacological relevance Withania somnifera (L.) Dunal (Solanaceae) is a
traditional herb, used in African indigenous systems of medicine for the treatment of various …
traditional herb, used in African indigenous systems of medicine for the treatment of various …
Vinegar-baked Radix Bupleuri enhances the liver-targeting effect of rhein on liver injury rats by regulating transporters
Y Zhao, J Wang, L Liu, Y Wu, Q Hu… - Journal of Pharmacy …, 2022 - academic.oup.com
Objective This study aimed to explore whether the liver-targeting enhancing effect of vinegar-
baked Radix Bupleuri (VBRB) on rhein was achieved by affecting transporters, metabolism …
baked Radix Bupleuri (VBRB) on rhein was achieved by affecting transporters, metabolism …
Saikosaponins and the deglycosylated metabolites exert liver meridian guiding effect through PXR/CYP3A4 inhibition
Q Liu, Y Xue, J Liu, S Ren, J Xu, J Yang, Y Xing… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Radix Bupleuri (RB), traditionally used to treat
inflammatory disorders and infectious diseases, represents one of the most successful and …
inflammatory disorders and infectious diseases, represents one of the most successful and …
[HTML][HTML] Exploring the potential of functional polymer-lipid hybrid nanoparticles for enhanced oral delivery of paclitaxel
L Qin, H Wu, E Xu, X Zhang, J Guan, R Zhao… - Asian Journal of …, 2021 - Elsevier
Most biopharmaceutics classification system (BCS) class IV drugs, with poor solubility and
inferior permeability, are also substrates of P-glycoprotein (P-gp) and cytochrome P450 …
inferior permeability, are also substrates of P-glycoprotein (P-gp) and cytochrome P450 …
Enhanced liver-targeting via coadministration of 10-Hydroxycamptothecin polymeric micelles with vinegar baked Radix Bupleuri
H Wu, T Yu, Y Tian, Y Wang, R Zhao, S Mao - Phytomedicine, 2018 - Elsevier
Abstract Background Vinegar baked Radix Bupleuri (VBRB) is a wildly used traditional
Chinese medicine, it could be used as a meridian guided drug to enhance liver targeting …
Chinese medicine, it could be used as a meridian guided drug to enhance liver targeting …
Validated UPLC-MS/MS method for simultaneous quantification of eight saikosaponins in rat plasma: Application to a comparative pharmacokinetic study in …
T Lei, D Zhang, K Guo, M Li, C Lv, J Wang, L Jia… - … of Chromatography B, 2017 - Elsevier
A sensitive and efficient UPLC–MS/MS method was developed and validated for
simultaneous quantification of eight saikosaponins (SSa, SSb 1, SSb 2, SSb 3, SSb 4, SSc …
simultaneous quantification of eight saikosaponins (SSa, SSb 1, SSb 2, SSb 3, SSb 4, SSc …