Investigating the neurobiology of maternal opioid use disorder and prenatal opioid exposure using brain organoid technology

I Dwivedi, GG Haddad - Frontiers in Cellular Neuroscience, 2024 - frontiersin.org
Over the past two decades, Opioid Use Disorder (OUD) among pregnant women has
become a major global public health concern. OUD has been characterized as a …

Extracellular vesicles—Mediators of opioid use disorder?

DC Morris, A Zacharek, ZG Zhang… - Addiction biology, 2023 - Wiley Online Library
Opioid use disorder (OUD) is a growing health emergency in the United States leading to an
epidemic of overdose deaths. OUD is recognized as an addictive brain disorder resulting in …

Sex and age effects on gray matter volume trajectories in young children with prenatal alcohol exposure

M Long, P Kar, ND Forkert, BA Landman… - Frontiers in Human …, 2024 - frontiersin.org
Prenatal alcohol exposure (PAE) occurs in~ 11% of North American pregnancies and is the
most common known cause of neurodevelopmental disabilities such as fetal alcohol …

Prenatal Opioid Exposure and Risk for Adverse Brain and Motor Outcomes in Infants Born Premature

EM Mahabee-Gittens, VSP Illapani, SL Merhar… - The Journal of …, 2024 - Elsevier
Objective To compare brain magnetic resonance imaging (MRI) biomarkers and
neurodevelopmental test scores in infants born preterm with and without prenatal opioid …

[HTML][HTML] Developmental implications of prenatal opioid exposure among school-aged children: a mixed methods and community-initiated analysis

A Wilkinson, HS Rackers, TM Harmon - BMC Public Health, 2023 - Springer
Background Growing research points to potential long-term developmental implications of
prenatal opioid exposure for children. Yet, polysubstance use and adverse childhood …

The Impact of Opium Consumption on Inflammatory Factors in Umbilical Cord Blood and Maternal Blood Postpartum: A Potential Contributor to Neonatal …

S Khayat, H Fanaei, F Riki… - Journal of Drug …, 2024 - journals.sagepub.com
Opium addiction during pregnancy can have significant effects on the activity of the immune
system as well as on pregnancy outcomes. A study was conducted comparing opium …

Children had increased risks of impaired motor and visual‐motor skills after prenatal exposure to opioid maintenance therapy

AK Aslaksen, ML Hoem, GH Vikesdal, MT Voie… - Acta …, 2024 - Wiley Online Library
Aim Preschool children prenatally exposed to opioid maintenance therapy (OMT) have an
increased risk of neurodevelopmental impairments. We aimed to investigate long‐term …

[HTML][HTML] A mini review of what matters in the management of NAS, is ESC the best care?

E Gomez Pomar - Frontiers in Pediatrics, 2023 - frontiersin.org
As the use of opioids and polysubstance by pregnant women has increased over the years,
there has also been a sharp increase in cases of neonatal abstinence syndrome (NAS) …

The children of the opioid epidemic: A mixed method examination of the developmental implications of prenatal opioid exposure among school-aged children

AL Wilkinson, HS Rackers, T Harmon - 2023 - researchsquare.com
Background Growing research points to potential long-term developmental implications of
prenatal opioid exposure for children. Yet, polysubstance use and adverse childhood …