Cryptorchidism and hypospadias as a sign of testicular dysgenesis syndrome (TDS): environmental connection

J Toppari, HE Virtanen, KM Main… - … Research Part A …, 2010 - Wiley Online Library
Cryptorchidism and hypospadias are common genital birth defects that affect 2–9% and 0.2–
1% of male newborns, respectively. The incidence of both defects shows large geographic …

Widely Used Pesticides with Previously Unknown Endocrine Activity Revealed as in Vitro Antiandrogens

F Orton, E Rosivatz, M Scholze… - Environmental health …, 2011 - ehp.niehs.nih.gov
Background Evidence suggests that there is widespread decline in male reproductive health
and that antiandrogenic pollutants may play a significant role. There is also a clear disparity …

Agrichemicals in surface water and birth defects in the United States

PD Winchester, J Huskins, J Ying - Acta paediatrica, 2009 - Wiley Online Library
Objectives: To investigate if live births conceived in months when surface water
agrichemicals are highest are at greater risk for birth defects. Methods: Monthly …

Low dose mixture effects of endocrine disrupters: implications for risk assessment and epidemiology

A Kortenkamp - International journal of andrology, 2008 - Wiley Online Library
During the last years, a series of studies on combinations of oestrogenic, thyroid‐disrupting
and anti‐androgenic chemicals at low doses have been published. The available …

Possible fetal determinants of male infertility

A Juul, K Almstrup, AM Andersson, TK Jensen… - Nature Reviews …, 2014 - nature.com
Although common reproductive problems, such as male infertility and testicular cancer,
present in adult life, strong evidence exists that these reproductive disorders might have a …

Effects of organochlorine pesticide residues in maternal body on infants

SY Qi, XL Xu, WZ Ma, SL Deng, ZX Lian… - Frontiers in …, 2022 - frontiersin.org
There are many organochlorine pollutants in the environment, which can be directly or
indirectly exposed to by mothers, and as estrogen endocrine disruptors can cause damage …

Is hypospadias associated with prenatal exposure to endocrine disruptors? A French collaborative controlled study of a cohort of 300 consecutive children without …

N Kalfa, F Paris, P Philibert, M Orsini, S Broussous… - European urology, 2015 - Elsevier
Background Numerous studies have focused on the association between endocrine-
disrupting chemicals (EDCs) and hypospadias. Phenotype variability, the absence of …

1, 1, 1-trichloro-2, 2-bis (p-chlorophenyl)-ethane (DDT) and 1, 1-Dichloro-2, 2-bis (p, p'-chlorophenyl) ethylene (DDE) as endocrine disruptors in human and wildlife: A …

MA Burgos-Aceves, V Migliaccio, I Di Gregorio… - Environmental …, 2021 - Elsevier
trichloro-2, 2-bis (p-chlorophenyl)-ethane (DDT) and its main metabolite 1, 1-Dichloro-2, 2-
bis (p, p'-chlorophenyl) ethylene (DDE) act as endocrine disruptors in humans and wildlife …

Persistent organochlorine pesticides and risk of testicular germ cell tumors

KA McGlynn, SM Quraishi, BI Graubard… - Journal of the …, 2008 - academic.oup.com
Background Exposure to endocrine-disrupting chemicals, such as persistent organochlorine
pesticides, has been suggested to increase the risk of testicular germ cell tumors (TGCTs) …

[HTML][HTML] Human infertility: are endocrine disruptors to blame?

A Marques-Pinto, D Carvalho - Endocrine connections, 2013 - ec.bioscientifica.com
Over recent decades, epidemiological studies have been reporting worrisome trends in the
incidence of human infertility rates. Extensive detection of industrial chemicals in human …