The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …

The vitamin D metabolite 1α, 25-dihydroxyvitamin D3 is the natural, high-affinity ligand of the
transcription factor vitamin D receptor (VDR). In many tissues and cell types, VDR binds in a …

Discovered many decades earlier by Mellanby, 1 McCollum and colleagues, 2 Steenbock, 3
and Windaus and colleagues, 4 vitamin D is now known through ensuing research efforts by …

The interest in vitamin D continues unabated with thousands of publications contributing to a
vast and growing literature each year. It is widely recognized that the vitamin D receptor …

Mesenchymal (stromal) stem cells (MSCs) constitute populations of mesodermal multipotent
cells involved in tissue regeneration and homeostasis in many different organs. Here we …

Over the past 2 decades, mesenchymal stem cells (MSCs) have attracted a lot of interest as
a unique therapeutic approach for a variety of diseases. MSCs are capable of self-renewal …

Accumulating evidence suggests that the therapeutic role of mesenchymal stem cells
(MSCs) in bone diseases is closely related to paracrine-generated extracellular vesicles …

Aging is accompanied by a general decline in the function of many cellular pathways.
However, whether these are causally or functionally interconnected remains elusive. Here …

The vitamin D receptor (VDR) is the single known regulatory mediator of hormonal 1, 25-
dihydroxyvitamin D3 [1, 25 (OH) 2D3] in higher vertebrates. It acts in the nucleus of vitamin D …

Background: Vitamin D exerts multiple beneficial effects in humans, including neuronal,
immune, and bone homeostasis and the regulation of cardiovascular functions. Recent …