Nucleoid-associated proteins typically are abundant, low-molecular-mass polypeptides that
bind DNA and alter its shape and its ability to participate in transactions such as …

Antibiotic resistance mediated by bacterial enzymes constitutes an unmet clinical challenge
for public health, particularly for those currently used antibiotics that are recognized as “last …

Shigella spp. cause hundreds of millions of intestinal infections each year. They target the
mucosa of the human colon and are an important model of intracellular bacterial …

Shigellosis is an acute invasive enteric infection by the Gram negative pathogen Shigella,
which causes human diarrhea. Shigella, which are highly epidemic and pathogenic, have …

Dickeya dadantii is a pathogen infecting a wide range of plant species. Soft rot, the visible
symptom, is mainly due to the production of pectate lyases (Pels) that can destroy the plant …

Shigella is a highly adapted human pathogen, mainly found in the developing world and
causing a severe enteric syndrome. The highly sophisticated infectious strategy of Shigella …

Shigella, the aetiological agent of human bacillary dysentery, controls the expression of its
virulence determinants through an environmentally stimulated cascade of transcriptional …

VirF is an AraC family transcriptional activator that is required for the expression of virulence
genes associated with invasion and cell-to-cell spread by Shigella flexneri, including …

Small RNAs (sRNAs) are important gene regulators in bacteria. Many sRNAs act post-
transcriptionally by affecting translation and degradation of the target mRNAs upon base …

Gram-negative enteropathogenic bacteria use a variety of strategies to cause disease in the
human host and gene regulation in some form is typically a part of the strategy. This article …