Although HIV-specific cellular immune responses are found in a number of HIV highly-
exposed, persistently seronegative (HEPS) cohorts, late seroconversion can occur despite …

ABSTRACT A major premise underlying current human immunodeficiency virus type 1 (HIV-
1) vaccine approaches is that preexisting HIV-1-specific immunity will block or reduce …

Human immunodeficiency virus type 1 (HIV-1) subtype C is the dominant subtype globally,
due largely to the incidence of subtype C infections in sub-Saharan Africa and east Asia. We …

Objectives: HIV-neutralizing immunoglobulin A (IgA) and HIV-specific cellular immunity have
been described in highly exposed, persistently seronegative (HEPS) individuals, but well …

Objective: To describe the response to highly active antiretroviral treatment (HAART) in a
public sector pilot antiretroviral (ARV) treatment program in Botswana. Methods: The …

Objective: To characterize the subtype C strains of HIV type 1 that circulate in Brazil,
especially those originated from the southern part of the country. Design and methods: One …

A major barrier to conducting HIV cure research in populations with the highest HIV burden
is the lack of an accurate assay to quantify the replication-competent reservoir across the …

It has been hypothesized that HIV-1 viral load set-point is a surrogate measure of HIV-1 viral
virulence, and that it may be subject to natural selection in the human host population. A key …

Genetic recombination is part of the normal mechanisms of retroviral replication and, as
such, plays an important role in the generation of viral diversity. Generation of recombinant …

Identifying naturally-occurring neutralizing antibodies (NAb) that are cross-reactive against
all global subtypes of HIV-1 is an important step toward the development of a vaccine …