Obesity and cancer risk: Emerging biological mechanisms and perspectives
Continuously rising trends in obesity-related malignancies render this disease spectrum a
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …
public health priority. Worldwide, the burden of cancer attributable to obesity, expressed as …
Obesity and breast cancer: a paradoxical and controversial relationship influenced by menopausal status
L García-Estévez, J Cortés, S Pérez, I Calvo… - Frontiers in …, 2021 - frontiersin.org
Breast cancer is the most common tumor in women worldwide, and an increasing public
health concern. Knowledge of both protective and negative risk factors is essential for a …
health concern. Knowledge of both protective and negative risk factors is essential for a …
[HTML][HTML] Body fatness associations with cancer: evidence from recent epidemiological studies and future directions
This narrative review highlights current evidence linking greater body fatness to risk of
various cancers, with focus on evidence from recent large cohort studies and pooled …
various cancers, with focus on evidence from recent large cohort studies and pooled …
Obesity and breast cancer: a case of inflamed adipose tissue
R Kolb, W Zhang - Cancers, 2020 - mdpi.com
Obesity is associated with an increased risk of estrogen receptor-positive breast cancer in
postmenopausal women and a worse prognosis for all major breast cancer subtypes …
postmenopausal women and a worse prognosis for all major breast cancer subtypes …
Adipose tissue, obesity and adiponectin: role in endocrine cancer risk
A Tumminia, F Vinciguerra, M Parisi… - International journal of …, 2019 - mdpi.com
Adipose tissue has been recognized as a complex organ with endocrine and metabolic
roles. The excess of fat mass, as occurs during overweight and obesity states, alters the …
roles. The excess of fat mass, as occurs during overweight and obesity states, alters the …
The role of adipokines in breast cancer: current evidence and perspectives
GS Christodoulatos, N Spyrou, J Kadillari… - Current obesity …, 2019 - Springer
Purpose The current review shows evidence for the role of adipokines in breast cancer (BC)
pathogenesis summarizing the mechanisms underlying the association between adipokines …
pathogenesis summarizing the mechanisms underlying the association between adipokines …
New horizons: epidemiology of obesity, diabetes mellitus, and cancer prognosis
S Harborg, KA Kjærgaard, RW Thomsen… - The Journal of …, 2024 - academic.oup.com
The global prevalence of obesity and diabetes mellitus has increased in parallel with
increasing cancer incidence, due to environmental and lifestyle factors and population …
increasing cancer incidence, due to environmental and lifestyle factors and population …
Updated clinical evidence on the role of adipokines and breast cancer: a review
Simple Summary Breast cancer is currently one of the most common types of cancer and the
number one cause of cancer-related deaths in women worldwide. Despite significant …
number one cause of cancer-related deaths in women worldwide. Despite significant …
Multifaceted effects of obesity on cancer immunotherapies: bridging preclinical models and clinical data
Obesity, defined by excessive body fat, is a highly complex condition affecting numerous
physiological processes, such as metabolism, proliferation, and cellular homeostasis. These …
physiological processes, such as metabolism, proliferation, and cellular homeostasis. These …
The impact of obesity, adipose tissue, and tumor microenvironment on macrophage polarization and metastasis
O Habanjar, M Diab-Assaf, F Caldefie-Chezet, L Delort - Biology, 2022 - mdpi.com
Simple Summary The inflammatory adipose microenvironment in obesity plays a crucial role
in cancer development and metastases. By focusing on adipocytes and macrophages, as …
in cancer development and metastases. By focusing on adipocytes and macrophages, as …