Advances in bladder cancer biology and therapy

L Tran, JF Xiao, N Agarwal, JE Duex… - Nature Reviews …, 2021 - nature.com
The field of research in bladder cancer has seen significant advances in recent years. Next-
generation sequencing has identified the genes most mutated in bladder cancer. This …

Current best practice for bladder cancer: a narrative review of diagnostics and treatments

E Compérat, MB Amin, R Cathomas, A Choudhury… - The Lancet, 2022 - thelancet.com
This Seminar presents the current best practice for the diagnosis and management of
bladder cancer. The scope of this Seminar ranges from current challenges in pathology …

An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer

SV Lindskrog, F Prip, P Lamy, A Taber… - Nature …, 2021 - nature.com
The molecular landscape in non-muscle-invasive bladder cancer (NMIBC) is characterized
by large biological heterogeneity with variable clinical outcomes. Here, we perform an …

European Association of Urology (EAU) prognostic factor risk groups for non–muscle-invasive bladder cancer (NMIBC) incorporating the WHO 2004/2016 and WHO …

RJ Sylvester, O Rodríguez, V Hernández, D Turturica… - European urology, 2021 - Elsevier
Abstract Background The European Association of Urology (EAU) prognostic factor risk
groups for non–muscle-invasive bladder cancer (NMIBC) are used to provide …

Practical recommendations for using ctDNA in clinical decision making

SA Cohen, MC Liu, A Aleshin - Nature, 2023 - nature.com
The continuous improvement in cancer care over the past decade has led to a gradual
decrease in cancer-related deaths. This is largely attributed to improved treatment and …

Recurrence mechanisms of non-muscle-invasive bladder cancer—A clinical perspective

JYC Teoh, AM Kamat, PC Black, P Grivas… - Nature Reviews …, 2022 - nature.com
Non-muscle-invasive bladder cancer (NMIBC) is an early-stage cancer without invasion into
the detrusor muscle layer. Transurethral resection of bladder tumour (TURBT) is a diagnostic …

Urinary MicroRNAs as biomarkers of urological cancers: a systematic review

A Aveta, S Cilio, R Contieri, G Spena… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs) are emerging as biomarkers for the detection and prognosis of
cancers due to their inherent stability and resilience. To summarize the evidence regarding …

Urine DNA methylation assay enables early detection and recurrence monitoring for bladder cancer

X Chen, J Zhang, W Ruan, M Huang… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Current methods for the detection and surveillance of bladder cancer (BCa)
are often invasive and/or possess suboptimal sensitivity and specificity, especially in early …

100 years of Bacillus Calmette–Guérin immunotherapy: from cattle to COVID-19

N Lobo, NA Brooks, AR Zlotta, JD Cirillo… - Nature Reviews …, 2021 - nature.com
Abstract Bacillus Calmette–Guérin (BCG) is the most widely used vaccine worldwide and
has been used to prevent tuberculosis for a century. BCG also stimulates an anti-tumour …

Integrated Urinalysis Devices Based on Interface‐Engineered Field‐Effect Transistor Biosensors Incorporated With Electronic Circuits

Y Yang, J Wang, W Huang, G Wan, M Xia… - Advanced …, 2022 - Wiley Online Library
Urinalysis is attractive in non‐invasive early diagnosis of bladder cancer compared with
clinical gold standard cystoscopy. However, the trace bladder tumor biomarkers in urine and …