Objectives: In the course of extensive clinical aortic surgery, we noticed that the aorta was
quite thick and fibrotic in diabetic patients. We thought the diabetic aortic aorta might be …

Abdominal aortic aneurysm (AAA) is defined as a permanent dilatation of the abdominal
aorta that exceeds 3 cm. Most AAAs arise in the portion of abdominal aorta distal to the renal …

Objective Mural angiogenesis and macrophage accumulation are two pathologic hallmarks
of abdominal aortic aneurysm (AAA) disease. The heterodimeric transcription factor hypoxia …

Background and aims We aimed at comprehensively evaluate the independent association
of diabetes and its duration with incident abdominal aortic aneurysm (AAA) and aortic …

Aortic pathologies such as aneurysm, dissection and trauma are relatively common and
potentially fatal diseases. Over the past two decades, we have experienced unprecedented …

Abdominal aortic aneurysm (AAA) is a vascular disease with high mortality. Because of the
lack of effective medications to stop or reverse the progression of AAA, surgical operation …

Introduction Abdominal aortic aneurysm (AAA) and coronary artery disease (CAD) share
common risk factors. The objective of this study was to determine the prevalence of …

Background This Mendelian randomization (MR) study aimed to explore the causal
relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and …

Abdominal aortic aneurysm (AAA) may lead to rupture and death if left untreated. While
endovascular or surgical repair is generally recommended for AAA greater than 5–5.5 cm …

Towler Sclerostin and Wnt/LRP Signaling in Arterial Disease 393 it provides additional
evidence that the Wnt/LRP signaling cascade can be pharmacologically targeted to …