Release of membrane vesicles, a process conserved in both prokaryotes and eukaryotes,
represents an evolutionary link, and suggests essential functions of a dynamic extracellular …

The lung is the organ with the highest vascular density in the human body. It is therefore
perceivable that the endothelium of the lung contributes significantly to the circulation of …

Membrane microparticles are submicron fragments of membrane shed into extracellular
space from cells under conditions of stress/injury. They may be distinguished from other …

Microvesicles (MVs) circulating in the blood are small vesicles (100–1,000 nm in diameter)
derived from membrane blebs of cells such as activated platelets, endothelial cells, and …

Microparticles are submicron vesicles shed from a variety of cells. Peter Wolf first identified
microparticles in the midst of ongoing blood coagulation research in 1967 as a product of …

Abstract The post-Pulmonary Embolism (post-PE) syndrome is being increasingly
recognized as a long-term consequence of PE. Its most severe manifestation, chronic …

Platelets can release a heterogeneous pool of vesicles which include plasma membrane-
derived microparticles (PMPs) and multivesicular body-derived exosomes. As both vesicle …

In the pulmonary vasculature, the endothelial and smooth muscle cells are two key cell types
that play a major role in the pathobiology of pulmonary vascular disease and pulmonary …

The ageing population continues to suffer from its primary killer, cardiovascular disease
(CVD). Despite recent advances in interventional medicinal and surgical therapies towards …

Microparticles (MP s), small membrane‐derived vesicles, are derived from many cell types
and released into the circulation. Microparticles can express antigens, and contain cell …