Endothelial dysfunction in pulmonary hypertension: cause or consequence?

K Kurakula, VFED Smolders, O Tura-Ceide… - Biomedicines, 2021 - mdpi.com
Pulmonary arterial hypertension (PAH) is a rare, complex, and progressive disease that is
characterized by the abnormal remodeling of the pulmonary arteries that leads to right …

Chronic obstructive pulmonary disease and atherosclerosis: common mechanisms and novel therapeutics

K Brassington, S Selemidis, S Bozinovski… - Clinical …, 2022 - portlandpress.com
Chronic obstructive pulmonary disease (COPD) and atherosclerosis are chronic irreversible
diseases, that share a number of common causative factors including cigarette smoking …

Endothelial dysfunction in COVID-19: a unifying mechanism and a potential therapeutic target

P Ambrosino, IL Calcaterra, M Mosella, R Formisano… - Biomedicines, 2022 - mdpi.com
The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) generated a
worldwide emergency, until the declaration of the pandemic in March 2020. SARS-CoV-2 …

[HTML][HTML] Naringin suppressed airway inflammation and ameliorated pulmonary endothelial hyperpermeability by upregulating Aquaporin1 in lipopolysaccharide …

H Zhang, X Zhou, Y Zhong, L Ji, W Yu, J Fang… - Biomedicine & …, 2022 - Elsevier
Naringin is one of the natural flavonoids extracted from many Chinese medicines. It
ameliorates endothelial dysfunctions in atherosclerosis, diabetes, and cardiovascular …

The role of IL-33/ST2 in COPD and its future as an antibody therapy

L Riera-Martínez, L Cànaves-Gómez, A Iglesias… - International journal of …, 2023 - mdpi.com
COPD is a leading cause of mortality and morbidity worldwide and is associated with a high
socioeconomic burden. Current treatment includes the use of inhaled corticosteroids and …

Association of COPD exacerbations and acute cardiovascular events: a systematic review and meta-analysis

H Müllerová, J Marshall, E De Nigris… - Therapeutic …, 2022 - journals.sagepub.com
Background: The majority of patients with chronic obstructive pulmonary disease (COPD)
suffer from comorbid cardiovascular (CV) disease. Accumulating evidence suggests a …

Role of IL-33-ST2 pathway in regulating inflammation: current evidence and future perspectives

Y Zhou, Z Xu, Z Liu - Journal of Translational Medicine, 2023 - Springer
Abstract Interleukin (IL)-33 is an alarmin of the IL-1 superfamily localized to the nucleus of
expressing cells, such as endothelial cells, epithelial cells, and fibroblasts. In response to …

The Effectiveness of Supplementation with Key Vitamins, Minerals, Antioxidants and Specific Nutritional Supplements in COPD—A Review

M Fekete, T Csípő, V Fazekas-Pongor, Á Fehér… - Nutrients, 2023 - mdpi.com
Currently, an increasing amount of evidence supports the notion that vitamins C, D and E,
carotenoids, and omega-3 fatty acids may protect against the progression of chronic …

Immunological insights into cigarette smoking-induced cardiovascular disease risk

A Dahdah, RM Jaggers, G Sreejit, J Johnson, B Kanuri… - Cells, 2022 - mdpi.com
Smoking is one of the most prominent addictions of the modern world, and one of the
leading preventable causes of death worldwide. Although the number of tobacco smokers is …

The combination of hemogram indexes to predict exacerbation in stable chronic obstructive pulmonary disease

X Liu, H Ge, X Feng, J Hang, F Zhang, X Jin… - Frontiers in …, 2020 - frontiersin.org
Background: Chronic obstructive pulmonary disease (COPD) is characterized by pulmonary
and systemic inflammatory processes, and exacerbation of COPD represents a critical …