[HTML][HTML] Dissecting the crosstalk between Nrf2 and NF-κB response pathways in drug-induced toxicity

W Gao, L Guo, Y Yang, Y Wang, S Xia… - Frontiers in cell and …, 2022 - frontiersin.org
Nrf2 and NF-κB are important regulators of the response to oxidative stress and
inflammation in the body. Previous pharmacological and genetic studies have confirmed …

Pharmacological significance of hesperidin and hesperetin, two citrus flavonoids, as promising antiviral compounds for prophylaxis against and combating COVID-19

PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Hesperidin and hesperetin are flavonoids that are abundantly present as constituents of
citrus fruits. These compounds have attracted attention as several computational methods …

Animal models of drug-induced pulmonary fibrosis: an overview of molecular mechanisms and characteristics

S Li, J Shi, H Tang - Cell Biology And Toxicology, 2022 - Springer
Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by
progressive loss of pulmonary function. Drug-induced interstitial lung disease has been …

The therapeutic role of nutraceuticals targeting the Nrf2/HO‐1 signaling pathway in liver cancer

KS Alharbi, WH Almalki, M Albratty… - Journal of Food …, 2022 - Wiley Online Library
Liver cancer (LC) is the most common cause of cancer death in the United States and the
fifth most common globally. The overexpression of nuclear factor E2 related factor 2 (Nrf2) …

[HTML][HTML] Therapeutic effects and molecular mechanisms of bioactive compounds against respiratory diseases: traditional Chinese medicine theory and high-frequency …

J Wang, Q Wu, L Ding, S Song, Y Li, L Shi… - Frontiers in …, 2021 - frontiersin.org
Respiratory diseases, especially the pandemic of respiratory infectious diseases and
refractory chronic lung diseases, remain a key clinical issue and research hot spot due to …

[HTML][HTML] Current update on role of hesperidin in inflammatory lung diseases: chemistry, pharmacology, and drug delivery approaches

S Hosawi - Life, 2023 - mdpi.com
Inflammation is a common feature of many respiratory diseases, such as pneumonia,
asthma, pulmonary fibrosis, chronic obstructive pulmonary disease (COPD), lung cancer …

Hesperidin inhibits lung fibroblast senescence via IL-6/STAT3 signaling pathway to suppress pulmonary fibrosis

D Han, H Gong, Y Wei, Y Xu, X Zhou, Z Wang, F Feng - Phytomedicine, 2023 - Elsevier
Background Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal lung
disease with obscure pathogenesis. Increasing evidence suggests that cellular senescence …

[HTML][HTML] Nutraceuticals in the Prevention of Viral Infections, including COVID-19, among the Pediatric Population: A Review of the Literature

GF Parisi, G Carota, C Castruccio Castracani… - International Journal of …, 2021 - mdpi.com
In recent years, there has been a growth in scientific interest in nutraceuticals, which are
those nutrients in foods that have beneficial effects on health. Nutraceuticals can be …

Roles of lipid metabolism and its regulatory mechanism in idiopathic pulmonary fibrosis: A review

Y Tian, C Duan, J Feng, J Liao, Y Yang… - The International Journal of …, 2023 - Elsevier
Idiopathic pulmonary fibrosis is a progressive lung disease of unknown etiology
characterized by distorted distal lung architecture, inflammation, and fibrosis. Several lung …

Naringin regulates endoplasmic reticulum stress and mitophagy through the ATF3/PINK1 signaling axis to alleviate pulmonary fibrosis

Y Wei, L Sun, C Liu, L Li - Naunyn-Schmiedeberg's Archives of …, 2023 - Springer
Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease that is
characterized by abnormal proliferation of fibroblasts and extracellular matrix remodeling …