In the 10 years since our previous International Union of Basic and Clinical Pharmacology
report on the nomenclature and classification of adenosine receptors, no developments …

Dopamine is an important neurotransmitter that plays a key role in neuropsychiatric illness.
Sex differences in dopaminergic signaling have been acknowledged for decades and have …

The adenosine A2A receptor is a G-protein-coupled receptor (GPCR) that has been
extensively studied during the past few decades because it offers numerous possibilities for …

Dopamine (DA) and DA receptors (DR) have been extensively studied in the central nervous
system (CNS), but their role in the periphery is still poorly understood. Here we summarize …

The inhibitory adenosine A1 receptor (A1R) and excitatory A2A receptor (A2AR) are
predominantly expressed in the brain. Whereas the A2AR has been implicated in normal …

We demonstrate a heteromeric D1–D2 dopamine receptor signaling complex in brain that is
coupled to Gq/11 and requires agonist binding to both receptors for G protein activation and …

Dopamine (DA) receptor, a significant G protein-coupled receptor, is classified into two
families: D1-like (D1 and D5) and D2-like (D2, D3, and D4) receptor families, with further …

The adenosine A 2A receptor has emerged as an attractive non-dopaminergic target in the
pursuit of improved therapy for Parkinson's disease (PD), based in part on its unique CNS …

Zea mays plasma membrane intrinsic proteins (ZmPIPs) fall into two groups, ZmPIP1s and
ZmPIP2s, that exhibit different water channel activities when expressed in Xenopus oocytes …

Increasing evidence suggests that regular consumption of coffee, tea and dark chocolate
(cacao) can promote brain health and may reduce the risk of age-related neurodegenerative …