Human diseases, especially infectious ones, have been evolving constantly. However, their
treatment strategies are not developing quickly. Some diseases are caused by a variety of …

In recent years, the advent of new experimental methodologies for studying the high
complexity of the human genome and proteome has led to the generation of an increasing …

PubChem's BioAssay database (https://pubchem. ncbi. nlm. nih. gov) has served as a public
repository for small-molecule and RNAi screening data since 2004 providing open access of …

中医药具有以整体观和辨证论治为特色的理论体系和几千年的临床实践经验,
中医药现代化亟需建立符合其整体特点的科学研究方法. 随着医学与生命科学研究步入大数据 …

Pandemic COVID-19 infections have spread throughout the world. There is no effective
treatment against this disease. Viral RNA-dependent RNA polymerase (RdRp) catalyzes the …

The beneficial effects of functionally useful plants (eg medicinal and food plants) arise from
the multi-target activities of multiple ingredients of these plants. The knowledge of the …

Public data from ECHA online dossiers on 9,801 substances encompassing 326,749
experimental key studies and additional information on classification and labeling were …

Dyslexia is a disorder characterized by an impaired ability to understand written and printed
words or phrases. Epidemiological longitudinal data show that dyslexia is highly prevalent …

Abstract Machine learning and deep learning approaches have been increasingly used in
the field of toxicology through prediction models developed using various toxicity data …

Experience in clinical practice and research in systems pharmacology suggested the
limitations of the current one-drug-one-target paradigm in new drug discovery. Single-target …