AIM To perform a comprehensive review and provide an up-to-date synopsis of the
incidence and trends of inflammatory bowel disease (IBD). METHODS We systematically …

Inflammatory bowel disease (IBD), as do most chronic inflammatory disorders, displays
unique features and confers different risk factors in male and female patients. Importantly …

Background & Aims Although the incidence of inflammatory bowel diseases (IBDs) varies
with age, few studies have examined variations between the sexes. We therefore used …

Background Primary immunodeficiencies (PIDs) are inherited diseases associated with a
considerable increase in susceptibility to infections. It is known that PIDs can also …

Objective We evaluated the influence of the renin–angiotensin system (RAS) on intestinal
inflammation and fibrosis. Design Cultured human colonic myofibroblast proliferation and …

Abstract Background and Aims Inflammatory bowel disease [IBD] is often one of the most
devastating and debilitating chronic gastrointestinal disorders in children and adolescents …

OBJECTIVES: Few data are available to describe the changes in incidence of pediatric-
onset inflammatory bowel disease (IBD). The aim of this study was to describe changes in …

IBD is a chronic disorder with disease onset ranging from early childhood to beyond the
sixth decade of life. The factors that determine the age of onset currently remain …

Current data indicate a change in the epidemiology of inflammatory bowel diseases. The
disease has become more widespread and the rise in the incidence has been reported in all …

Background Elderly patients represent an increasing proportion of the inflammatory bowel
disease (IBD) population. Aim To critically review available data regarding the care of …