Cytotoxicity of metal‐based nanoparticles: from mechanisms and methods of evaluation to pathological manifestations

P Xiong, X Huang, N Ye, Q Lu, G Zhang… - Advanced …, 2022 - Wiley Online Library
Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐,
drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex …

Toxicity of Nano-Titanium Dioxide (TiO2-NP) Through Various Routes of Exposure: a Review

M Shakeel, F Jabeen, S Shabbir, MS Asghar… - Biological trace element …, 2016 - Springer
Abstract Nano-titanium dioxide (TiO 2) is one of the most commonly used materials being
synthesized for use as one of the top five nanoparticles. Due to the extensive application of …

[HTML][HTML] Titanium dioxide nanoparticles: a review of current toxicological data

H Shi, R Magaye, V Castranova, J Zhao - Particle and fibre toxicology, 2013 - Springer
Abstract Titanium dioxide (TiO 2) nanoparticles (NPs) are manufactured worldwide in large
quantities for use in a wide range of applications. TiO 2 NPs possess different …

Critical review of public health regulations of titanium dioxide, a human food additive

B Jovanović - Integrated environmental assessment and …, 2015 - Wiley Online Library
From 1916 to 2011, an estimated total of 165 050 000 metric tons of titanium dioxide (TiO2)
pigment were produced worldwide. Current safety regulations on the usage of the TiO2 …

[HTML][HTML] Immunotoxicity of metal and metal oxide nanoparticles: from toxic mechanisms to metabolism and outcomes

J Bi, C Mo, S Li, M Huang, Y Lin, P Yuan, Z Liu… - Biomaterials …, 2023 - pubs.rsc.org
The influence of metal and metal oxide nanomaterials on various fields since their discovery
has been remarkable. They have unique properties, and therefore, have been employed in …

Size dependent biodistribution and toxicokinetics of iron oxide magnetic nanoparticles in mice

L Yang, H Kuang, W Zhang, ZP Aguilar, Y Xiong, W Lai… - Nanoscale, 2015 - pubs.rsc.org
In spite of the immense benefits from iron oxide magnetic nanoparticles (IOMNs), there is
scanty information regarding their metabolic activities and toxicity in vivo. In this study, we …

Oral, short-term exposure to titanium dioxide nanoparticles in Sprague-Dawley rat: focus on reproductive and endocrine systems and spleen

R Tassinari, F Cubadda, G Moracci, F Aureli… - …, 2014 - Taylor & Francis
The study explored possible reproductive and endocrine effects of short-term (5 days) oral
exposure to anatase TiO2 nanoparticles (0, 1, 2 mg/kg body weight per day) in rat …

Ovarian dysfunction and gene-expressed characteristics of female mice caused by long-term exposure to titanium dioxide nanoparticles

G Gao, Y Ze, B Li, X Zhao, T Zhang, L Sheng… - Journal of hazardous …, 2012 - Elsevier
Although numerous studies have described the accumulation of titanium dioxide
nanoparticles (TiO2 NPs) in the liver, kidneys, lung, spleen, and brain, and the …

Cytotoxicity, DNA damage, and apoptosis induced by titanium dioxide nanoparticles in human non-small cell lung cancer A549 cells

Y Wang, H Cui, J Zhou, F Li, J Wang, M Chen… - … Science and Pollution …, 2015 - Springer
Concerns about the risk of titanium dioxide nanoparticles (TiO 2 NPs) to human health and
environment are gradually increasing due to their wide range of applications. In this study …

[HTML][HTML] TiO2 nanoparticles cause mitochondrial dysfunction, activate inflammatory responses, and attenuate phagocytosis in macrophages: A proteomic and …

Q Chen, N Wang, M Zhu, J Lu, H Zhong, X Xue, S Guo… - Redox biology, 2018 - Elsevier
Abstract Titanium dioxide nanoparticles (TiO 2 NPs) are widely used in food and cosmetics
but the health impact of human exposure remains poorly defined. Emerging evidence …