A century of BCG: Impact on tuberculosis control and beyond

A Ahmed, S Rakshit, V Adiga, M Dias… - Immunological …, 2021 - Wiley Online Library
BCG turns 100 this year and while it might not be the perfect vaccine, it has certainly
contributed significantly towards eradication and prevention of spread of tuberculosis (TB) …

[HTML][HTML] Metabolic regulation of immune responses to mycobacterium tuberculosis: A spotlight on l-arginine and l-tryptophan metabolism

RR Crowther, JE Qualls - Frontiers in Immunology, 2021 - frontiersin.org
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a leading
cause of death worldwide. Despite decades of research, there is still much to be uncovered …

A Combinatorial Library of Lipid Nanoparticles for Cell Type‐Specific mRNA Delivery

GS Naidu, SB Yong, S Ramishetti… - Advanced …, 2023 - Wiley Online Library
Ionizable lipid‐based nanoparticles (LNPs) are the most advanced non‐viral drug delivery
systems for RNA therapeutics and vaccines. However, cell type‐specific, extrahepatic mRNA …

Beyond memory T cells: mechanisms of protective immunity to tuberculosis infection

P Steigler, AJ Verrall, JR Kirman - Immunology and cell biology, 2019 - Wiley Online Library
Tuberculosis (TB) is a serious infectious disease caused by infection with Mycobacterium
tuberculosis, and kills more people annually than any other single infectious agent. Although …

[HTML][HTML] Physiological estrogen levels are dispensable for the sex difference in immune responses during allergen-induced airway inflammation

A Barrett, P Humeniuk, C Drevinge, C Corciulo… - Immunobiology, 2023 - Elsevier
Women show an increased prevalence of adult-onset asthma compared to men and
previous studies have shown that testosterone inhibits while estrogen worsens allergen …

TNFRp75‐dependent immune regulation of alveolar macrophages and neutrophils during early Mycobacterium tuberculosis and Mycobacterium bovis BCG infection

A Walters, R Keeton, A Labuschagne, NJ Hsu… - …, 2021 - Wiley Online Library
TNF signalling through TNFRp55 and TNFRp75, and receptor shedding is important for
immune activation and regulation. TNFRp75 deficiency leads to improved control of …

Early innate immunity against mycobacterial infection

BM Ryder - 2021 - ourarchive.otago.ac.nz
Infection by Mycobacterium tuberculosis is not consistently prevented by the only licensed
vaccine, bacillus Calmette-Guérin (BCG). It is widely believed that adaptive immune memory …

Early innate phagocytic response to Mycobacterium bovis BCG

N Krotky - 2020 - phaidra.vetmeduni.ac.at
Tuberculosis is an infectious disease which is caused by the bacterium called
Mycobacterium tuberculosis and can develop anywhere in the body but occurs primarily as …

Growth Inhibition of Mycobacteria by Innate Lymphoid Cells

SJ Waller - 2019 - ourarchive.otago.ac.nz
Tuberculosis (TB) is a lung disease caused by Mycobacterium tuberculosis (Mtb), which was
responsible for 1.6 million deaths in 2017. The only vaccine against TB; bacille Calmette …