The roles of matrix metalloproteinases and their inhibitors in human diseases
GA Cabral-Pacheco, I Garza-Veloz… - International journal of …, 2020 - mdpi.com
Matrix metalloproteinases (MMPs) are a family of zinc-dependent extracellular matrix (ECM)
remodeling endopeptidases that have the capacity to degrade almost every component of …
remodeling endopeptidases that have the capacity to degrade almost every component of …
Impact of hypertension on retinal capillary microvasculature using optical coherence tomographic angiography
Objective: Reduction in capillary density or rarefaction is a hallmark of essential
hypertension. We measured the retinal capillary density using noninvasive optical …
hypertension. We measured the retinal capillary density using noninvasive optical …
Characterization of a mouse model of obesity-related fibrotic cardiomyopathy that recapitulates features of human heart failure with preserved ejection fraction
Heart failure with preserved ejection fraction (HFpEF) is caused, or exacerbated by, a wide
range of extracardiac conditions. Diabetes, obesity, and metabolic dysfunction are …
range of extracardiac conditions. Diabetes, obesity, and metabolic dysfunction are …
Echocardiographic advances in dilated cardiomyopathy
A Faggiano, C Avallone, D Gentile… - Journal of Clinical …, 2021 - mdpi.com
Although the overall survival of patients with dilated cardiomyopathy (DCM) has improved
significantly in the last decades, a non-negligible proportion of DCM patients still shows an …
significantly in the last decades, a non-negligible proportion of DCM patients still shows an …
Markers of focal and diffuse nonischemic myocardial fibrosis are associated with adverse cardiac remodeling and prognosis in patients with hypertension: the …
Background: The prognostic significance of focal and diffuse myocardial fibrosis in patients
with cardiovascular risk factors is unclear. Methods: REMODEL (Response of the …
with cardiovascular risk factors is unclear. Methods: REMODEL (Response of the …
Dihydromyricetin attenuates myocardial hypertrophy induced by transverse aortic constriction via oxidative stress inhibition and SIRT3 pathway enhancement
Y Chen, HQ Luo, LL Sun, MT Xu, J Yu, LL Liu… - International Journal of …, 2018 - mdpi.com
Dihydromyricetin (DMY), one of the flavonoids in vine tea, exerts several pharmacological
actions. However, it is not clear whether DMY has a protective effect on pressure overload …
actions. However, it is not clear whether DMY has a protective effect on pressure overload …
Echocardiographic global longitudinal strain is associated with myocardial fibrosis and predicts outcomes in aortic stenosis
Aims: Left ventricular ejection fraction is the conventional measure used to guide heart
failure management, regardless of underlying etiology. Left ventricular global longitudinal …
failure management, regardless of underlying etiology. Left ventricular global longitudinal …
Distribution of myocardial work in arterial hypertension: insights from non-invasive left ventricular pressure-strain relations
F Loncaric, M Marciniak, L Nunno, M Mimbrero… - The international journal …, 2021 - Springer
A index of non-invasive myocardial work (MWI) can account for pressure during the
assessment of cardiac function, potentially separating the influence of loading conditions …
assessment of cardiac function, potentially separating the influence of loading conditions …
Impact of systemic vascular risk factors on the choriocapillaris using optical coherence tomography angiography in patients with systemic hypertension
We investigated the characteristics of the choriocapillaris flow voids using optical coherence
tomography angiography (OCTA) in 85 patients (164 eyes) with hypertension (mean±SD …
tomography angiography (OCTA) in 85 patients (164 eyes) with hypertension (mean±SD …
Choriocapillaris microvasculature dysfunction in systemic hypertension
We examined the choriocapillaris microvasculature using a non-invasive swept-source
optical coherence tomography angiography (SS-OCTA) in 41 healthy controls and 71 …
optical coherence tomography angiography (SS-OCTA) in 41 healthy controls and 71 …