Systemic treatment of adult atopic dermatitis: a review

M Megna, M Napolitano, C Patruno, A Villani… - Dermatology and …, 2017 - Springer
Atopic dermatitis (AD) is a common chronic inflammatory skin disease that predominantly
affects children. However, it can persist in adulthood and/or start at older ages. Due to its …

Quorum sensing between bacterial species on the skin protects against epidermal injury in atopic dermatitis

MR Williams, SK Costa, LS Zaramela, S Khalil… - Science translational …, 2019 - science.org
Colonization of the skin by Staphylococcus aureus is associated with exacerbation of atopic
dermatitis (AD), but any direct mechanism through which dysbiosis of the skin microbiome …

Efficacy and safety of abrocitinib and upadacitinib versus dupilumab in adults with moderate-to-severe atopic dermatitis: A systematic review and meta-analysis

Q Gao, Y Zhao, J Zhang - Heliyon, 2023 - cell.com
Background: The sparsity of head-to-head trials for medications used as in atopic dermatitis
(AD) treatment makes therapy options difficult. Objective: To better compare the efficacy and …

Sézary syndrome and atopic dermatitis: comparison of immunological aspects and targets

I Saulite, W Hoetzenecker, S Weidinger… - BioMed research …, 2016 - Wiley Online Library
Sézary syndrome (SS), an aggressive form of erythrodermic pruritic cutaneous T cell
lymphoma (CTCL), from an immunological perspective characterized by increased Th2 …

Investigational drugs for atopic dermatitis

KL Hon, AKC Leung, TNH Leung… - Expert Opinion on …, 2018 - Taylor & Francis
Introduction: Many novel medications and herbal medicines have claimed efficacy on atopic
dermatitis (AD). Areas covered: This review covers evidence on efficacy of topical and oral …

Experimental drugs with the potential to treat atopic eczema

KLE Hon, VPY Chan, AKC Leung - Journal of experimental …, 2021 - Taylor & Francis
Introduction Eczema or atopic dermatitis (AD) is a chronically relapsing dermatosis
characterized by pruritus and a significant impact on the quality of life. Methods The authors …

The Effect of Osthole on Transient Receptor Potential Channels: A Possible Alternative Therapy for Atopic Dermatitis

NK Kordulewska, A Król-Grzymała - Journal of Inflammation …, 2024 - Taylor & Francis
Introduction Chronic recurrent skin inflammation and severe itching in patients with atopic
dermatitis (AD) significantly impair their quality of life. The H4 histamine receptor plays a key …

Inhibitory Effect of Mistletoe Ointment on DNCB-Induced Atopic Dermatitis in BALB/c Mice

CE Hong, SY Lyu - Scientia Pharmaceutica, 2023 - mdpi.com
Atopic dermatitis (AD) is increasingly prevalent globally. However, the frequent and
prolonged use of corticosteroids, which are commonly employed for AD treatment, carries …

Topical E6005/RVT-501, a novel phosphodiesterase 4 inhibitor, for the treatment of atopic dermatitis

M Furue, T Kadono, G Tsuji… - Expert Opinion on …, 2017 - Taylor & Francis
Introduction: Local adverse effects of steroid use and the burning sensation of calcineurin
inhibitors impair patients' adherence to treatment and decrease the treatment response in …

An overview of drug discovery efforts for eczema: why is this itch so difficult to scratch?

KL Hon, S Loo, AKC Leung, JTS Li… - Expert Opinion on Drug …, 2020 - Taylor & Francis
Introduction: Atopic dermatitis (AD) is a type of allergic/inflammatory dermatitis characterized
by itch and an impairment in quality of life. Areas covered: Herein, the authors review drug …