The role of miRNAs in insulin resistance and diabetic macrovascular complications–A review
Diabetes is the most prevalent metabolic disturbance disease and has been regarded
globally as one of the principal causes of mortality. Diabetes is accompanied by several …
globally as one of the principal causes of mortality. Diabetes is accompanied by several …
Tirzepatide, a new era of dual-targeted treatment for diabetes and obesity: a mini-review
The prevalence of obesity and diabetes is an increasing global problem, especially in
developed countries, and is referred to as the twin epidemics. As such, advanced treatment …
developed countries, and is referred to as the twin epidemics. As such, advanced treatment …
Dietary polyphenols as natural inhibitors of α-amylase and α-glucosidase
I Ćorković, D Gašo-Sokač, A Pichler, J Šimunović… - Life, 2022 - mdpi.com
It is well known that carbohydrates are the main source of calories in most diets. However,
by inhibiting carbohydrases, intake of calories is reduced and weight loss is improved. α …
by inhibiting carbohydrases, intake of calories is reduced and weight loss is improved. α …
A review on the green synthesis of benzimidazole derivatives and their pharmacological activities
M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …
Self‐Powered Syringe Pump for Insulin Pump Therapy Based on High‐Voltage Triboelectric Nanogenerator and Dielectric Elastomer Actuator
Insulin pump therapy (IPT) is commonly utilized for treating type 1 diabetes. However, the
insulin pump is generally rigid, and its prolonged use can cause discomfort to patients …
insulin pump is generally rigid, and its prolonged use can cause discomfort to patients …
Understanding the role of hyperglycemia and the molecular mechanism associated with diabetic neuropathy and possible therapeutic strategies
Diabetic neuropathy is a neuro-degenerative disorder that encompasses numerous factors
that impact peripheral nerves in the context of diabetes mellitus (DM). Diabetic peripheral …
that impact peripheral nerves in the context of diabetes mellitus (DM). Diabetic peripheral …
Polymeric micelles loaded with glyburide and vanillic acid: I. Formulation development, in-vitro characterization and bioavailability studies
The co-formulation of glyburide (Gly) and vanillic acid (VA) as such in the form of
nanomedicine has never been explored to treat metabolic diseases including type 2 …
nanomedicine has never been explored to treat metabolic diseases including type 2 …
Polyphenols-rich polyherbal mixture attenuates hepatorenal impairment, dyslipidaemia, oxidative stress and inflammation in alloxan-induced diabetic rats
B Aslam, A Hussain, ZUD Sindhu, S Nigar… - Journal of Applied …, 2023 - Taylor & Francis
Effects of polyherbal mixture on hepatorenal injury and dyslipidaemia in alloxan-induced
diabetic rats were evaluated. Alloxan monohydrate (120 mg/kg, ip) was injected into Wistar …
diabetic rats were evaluated. Alloxan monohydrate (120 mg/kg, ip) was injected into Wistar …
Design, synthesis, spectroscopic characterization, single crystal X-ray analysis, in vitro α-amylase inhibition assay, DPPH free radical evaluation and computational …
In our quest to design and develop N/O-containing inhibitors of α-amylase, we have tried to
synergize the inhibitory action of 1, 4-naphthoquinone, imidazole and 1, 2, 3-triazole motifs …
synergize the inhibitory action of 1, 4-naphthoquinone, imidazole and 1, 2, 3-triazole motifs …
Brazilin: biological activities and therapeutic potential in chronic degenerative diseases and cancer
DA Nava-Tapia, L Cayetano-Salazar… - Pharmacological …, 2022 - Elsevier
Caesalpinia sappan and Haematoxylum brasiletto belong to the Fabaceae family,
predominantly distributed in Southeast Asia and America. The isoflavonoid brazilin has …
predominantly distributed in Southeast Asia and America. The isoflavonoid brazilin has …