Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021 - Wiley Online Library
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …

Multi-targeted therapy of cancer by genistein

S Banerjee, Y Li, Z Wang, FH Sarkar - Cancer letters, 2008 - Elsevier
Soy isoflavones have been identified as dietary components having an important role in
reducing the incidence of breast and prostate cancers in Asian countries. Genistein, the …

History and development of radiation-protective agents

JF Weiss, MR Landauer - International journal of radiation biology, 2009 - Taylor & Francis
Purpose: The search for ideal protective agents for use in a variety of radiation scenarios
has continued for more than six decades. This review evaluates agents and procedures that …

Genistein: Dual role in women's health

L Yu, E Rios, L Castro, J Liu, Y Yan, D Dixon - Nutrients, 2021 - mdpi.com
Advanced research in recent years has revealed the important role of nutrients in the
protection of women's health and in the prevention of women's diseases. Genistein is a …

Using chemopreventive agents to enhance the efficacy of cancer therapy

FH Sarkar, Y Li - Cancer Research, 2006 - AACR
Emerging evidence suggests that cancer preventative agents might be combined with
chemotherapy or radiotherapy for the more effective treatment of cancer. Recent studies …

Soy isoflavones in integrative oncology: increased efficacy and decreased toxicity of cancer therapy

I Sahin, B Bilir, S Ali, K Sahin… - Integrative cancer …, 2019 - journals.sagepub.com
Soy consumption in human diet has been linked to decreased incidence of a variety of
cancers, suggesting a potential role of soy products in cancer prevention and control …

Genistein inhibits radiation-induced activation of NF-κB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest

JJ Raffoul, Y Wang, O Kucuk, JD Forman, FH Sarkar… - BMC cancer, 2006 - Springer
Background New cancer therapeutic strategies must be investigated that enhance prostate
cancer treatment while minimizing associated toxicities. We have previously shown that …

The role of natural polyphenols in the prevention and treatment of cervical cancer—An overview

MA Moga, OG Dimienescu, CA Arvatescu, A Mironescu… - Molecules, 2016 - mdpi.com
Cervical cancer represents the second leading cause of death for women worldwide. The
importance of the diet and its impact on specific types of neoplasia has been highlighted …

The role of signaling pathways in cervical cancer and molecular therapeutic targets

J Manzo-Merino, A Contreras-Paredes… - Archives of medical …, 2014 - Elsevier
Cervical cancer is a public health issue in developing countries. Although the Pap smear
and colposcopy remain the major strategies for detection, most cases are diagnosed in the …

Pancreatic cancer: pathogenesis, prevention and treatment

FH Sarkar, S Banerjee, Y Li - Toxicology and applied pharmacology, 2007 - Elsevier
Pancreatic cancer is the fourth leading cause of cancer death in the United States with a
very low survival rate of 5 years. To better design new preventive and/or therapeutic …