[HTML][HTML] Oncolytic virotherapy: basic principles, recent advances and future directions

D Lin, Y Shen, T Liang - Signal transduction and targeted therapy, 2023 - nature.com
Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …

[HTML][HTML] Mechanisms of metabolic reprogramming in cancer cells supporting enhanced growth and proliferation

C Schiliro, BL Firestein - Cells, 2021 - mdpi.com
Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth
and proliferation. These metabolic alterations include (1) a shift from oxidative …

[HTML][HTML] Mechanisms for modulating anoikis resistance in cancer and the relevance of metabolic reprogramming

FO Adeshakin, AO Adeshakin, LO Afolabi, D Yan… - Frontiers in …, 2021 - frontiersin.org
The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function
stability and well-being. ECM detachment in localized tumors precedes abnormal …

[HTML][HTML] To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

Unraveling tumor microenvironment of small-cell lung cancer: Implications for immunotherapy

T Li, T Qiao - Seminars in cancer biology, 2022 - Elsevier
Small-cell lung cancer (SCLC) is an aggressive lung cancer subtype and its first-line
treatment has remained unchanged for decades. In recent years, immunotherapy has …

[HTML][HTML] Steroidal saponins: naturally occurring compounds as inhibitors of the hallmarks of cancer

S Bouabdallah, A Al-Maktoum, A Amin - Cancers, 2023 - mdpi.com
Simple Summary Cancer is one of the most life-threatening diseases that affects a rapidly
growing number of individuals worldwide. Currently, chemotherapy is the most common …

[HTML][HTML] Advancing cancer treatment by targeting glutamine metabolism—A roadmap

A Halama, K Suhre - Cancers, 2022 - mdpi.com
Simple Summary Dysregulated glutamine metabolism is one of the metabolic features
evident in cancer cells when compared to normal cells. Cancer cells utilize glutamine for …

[HTML][HTML] GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy

A Mukha, U Kahya, A Linge, O Chen, S Löck… - Theranostics, 2021 - ncbi.nlm.nih.gov
Radiotherapy is one of the curative treatment options for localized prostate cancer (PCa).
The curative potential of radiotherapy is mediated by irradiation-induced oxidative stress …

Glutamine metabolism in breast cancer and possible therapeutic targets

S Li, H Zeng, J Fan, F Wang, C Xu, Y Li, J Tu… - Biochemical …, 2023 - Elsevier
Cancer is characterized by metabolic reprogramming, which is a hot topic in tumor treatment
research. Cancer cells alter metabolic pathways to promote their growth, and the common …

Metabolic dependencies and targets in ovarian cancer

Y Zhang, Y Wang, G Zhao, S Orsulic, D Matei - Pharmacology & …, 2023 - Elsevier
Reprogramming of cellular metabolism is a hallmark of cancer. Cancer cells undergo
metabolic adaptations to maintain tumorigenicity and survive under the attack of immune …