[HTML][HTML] Oncolytic virotherapy: basic principles, recent advances and future directions
D Lin, Y Shen, T Liang - Signal transduction and targeted therapy, 2023 - nature.com
Oncolytic viruses (OVs) have attracted growing awareness in the twenty-first century, as they
are generally considered to have direct oncolysis and cancer immune effects. With the …
are generally considered to have direct oncolysis and cancer immune effects. With the …
[HTML][HTML] Mechanisms of metabolic reprogramming in cancer cells supporting enhanced growth and proliferation
C Schiliro, BL Firestein - Cells, 2021 - mdpi.com
Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth
and proliferation. These metabolic alterations include (1) a shift from oxidative …
and proliferation. These metabolic alterations include (1) a shift from oxidative …
[HTML][HTML] Mechanisms for modulating anoikis resistance in cancer and the relevance of metabolic reprogramming
FO Adeshakin, AO Adeshakin, LO Afolabi, D Yan… - Frontiers in …, 2021 - frontiersin.org
The attachment of cells to the extracellular matrix (ECM) is the hallmark of structure–function
stability and well-being. ECM detachment in localized tumors precedes abnormal …
stability and well-being. ECM detachment in localized tumors precedes abnormal …
[HTML][HTML] To metabolomics and beyond: a technological portfolio to investigate cancer metabolism
F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …
Unraveling tumor microenvironment of small-cell lung cancer: Implications for immunotherapy
T Li, T Qiao - Seminars in cancer biology, 2022 - Elsevier
Small-cell lung cancer (SCLC) is an aggressive lung cancer subtype and its first-line
treatment has remained unchanged for decades. In recent years, immunotherapy has …
treatment has remained unchanged for decades. In recent years, immunotherapy has …
[HTML][HTML] Steroidal saponins: naturally occurring compounds as inhibitors of the hallmarks of cancer
S Bouabdallah, A Al-Maktoum, A Amin - Cancers, 2023 - mdpi.com
Simple Summary Cancer is one of the most life-threatening diseases that affects a rapidly
growing number of individuals worldwide. Currently, chemotherapy is the most common …
growing number of individuals worldwide. Currently, chemotherapy is the most common …
[HTML][HTML] Advancing cancer treatment by targeting glutamine metabolism—A roadmap
Simple Summary Dysregulated glutamine metabolism is one of the metabolic features
evident in cancer cells when compared to normal cells. Cancer cells utilize glutamine for …
evident in cancer cells when compared to normal cells. Cancer cells utilize glutamine for …
[HTML][HTML] GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy
Radiotherapy is one of the curative treatment options for localized prostate cancer (PCa).
The curative potential of radiotherapy is mediated by irradiation-induced oxidative stress …
The curative potential of radiotherapy is mediated by irradiation-induced oxidative stress …
Glutamine metabolism in breast cancer and possible therapeutic targets
S Li, H Zeng, J Fan, F Wang, C Xu, Y Li, J Tu… - Biochemical …, 2023 - Elsevier
Cancer is characterized by metabolic reprogramming, which is a hot topic in tumor treatment
research. Cancer cells alter metabolic pathways to promote their growth, and the common …
research. Cancer cells alter metabolic pathways to promote their growth, and the common …
Metabolic dependencies and targets in ovarian cancer
Reprogramming of cellular metabolism is a hallmark of cancer. Cancer cells undergo
metabolic adaptations to maintain tumorigenicity and survive under the attack of immune …
metabolic adaptations to maintain tumorigenicity and survive under the attack of immune …