Destruction of the periodontium is normally associated with periodontal disease, although
many other factors, such as trauma, aging, infections, orthodontic tooth movement and …

To meet the growing need for tissue replacement materials for our aging population, the
development of new adaptive biomaterials is essential. The tissues with the highest demand …

This second edition of the Bone Mechanics Handbook summarizes the current
understanding of bone mechanics with comprehensive coverage of the histology …

Acidic matrix macromolecules involved in regulation of biological crystal growth often
contain aspartic acid-rich domains and covalently bound sulfated polysaccharides. We …

Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …

Improved technologies have led to the isolation of a large number of noncollagenous matrix
proteins from the mineralized connective tissues. These proteins have been postulated to …

Proteoglycans consist of core proteins and one or more covalently-linked
glycosaminoglycan chains. They are structurally complex and heterogeneous …

Biomineralization describes the deposition of mineral within or outside the cells of living
organisms. Examples include iron and gold deposits in bacteria and other unicellular …

The predominant proteoglycans present in predentin and dentin are the chondroitin-
sulphate-rich decorin and biglycan and the keratan-sulphate-rich lumican and fibromodulin …

The small leucine-rich bone proteoglycans, biglycan and decorin, can be purified by
chromatography on hydroxyapatite columns, demonstrating their potential affinities for bone …