Wip1 inhibits neutrophil extracellular traps to promote abscess formation in mice by directly dephosphorylating Coronin-1a

Y Chen, C Zhao, H Guo, W Zou, Z Zhang… - Cellular & Molecular …, 2023 - nature.com
Neutrophil extracellular traps (NETs) participate in the rapid inhibition and clearance of
pathogens during infection; however, the molecular regulation of NET formation remains …

TRAPPC1 is essential for the maintenance and differentiation of common myeloid progenitors in mice

Y Xu, Z Zhang, Y Zhao, C Zhao, M Shi, X Dong… - EMBO …, 2023 - embopress.org
Myeloid cell development in bone marrow is essential for the maintenance of peripheral
immune homeostasis. However, the role of intracellular protein trafficking pathways during …

The Proteostasis of Thymic Stromal Cells in Health and Diseases

T Liu, S Xia - The Protein Journal, 2024 - Springer
The thymus is the key immune organ for the development of T cells. Different populations of
thymic stromal cells interact with T cells, thereby controlling the dynamic development of T …

Trappc1 intrinsically prevents ferroptosis of naive T cells to avoid spontaneous autoinflammatory disease in mice

Z Zhang, C Zhao, L Sun, C Cheng… - European Journal of …, 2024 - Wiley Online Library
T lymphocytes are pivotal in adaptive immunity. The role of the trafficking protein particle
complex (TRAPPC) in regulating T‐cell development and homeostasis is unknown. Using …

Biochemical Structure and Function of TRAPP Complexes in the Cardiac System

P Papaioannou, MJ Wallace, N Malhotra… - Basic to Translational …, 2023 - jacc.org
Trafficking protein particle (TRAPP) is well reported to play a role in the trafficking of protein
products within the Golgi and endoplasmic reticulum. Dysfunction in TRAPP has been …