Recent development of aryl diazonium chemistry for the derivatization of aromatic compounds

F Mo, D Qiu, L Zhang, J Wang - Chemical Reviews, 2021 - ACS Publications
Aryl diazonium salts are versatile building blocks in organic synthesis. In light of the ever-
increasing importance of aryl diazonium salts spanning most disciplines of the chemical …

Enroute sustainability: metal free C–H bond functionalisation

S Roy, S Panja, SR Sahoo, S Chatterjee… - Chemical Society …, 2023 - pubs.rsc.org
The term “C–H functionalisation” incorporates C–H activation followed by its transformation.
In a single line, this can be defined as the conversion of carbon–hydrogen bonds into …

Recent Advances in the Synthesis of C2‐Functionalized Pyridines and Quinolines Using N‐Oxide Chemistry

D Wang, L Désaubry, G Li, M Huang… - Advanced Synthesis & …, 2021 - Wiley Online Library
While remarkable progress has recently been made for the direct C− H‐functionalization of
azines, its application is still limited by a lack of accessible functional groups (primarily …

TsCl-promoted sulfonylation of quinoline N-oxides with sodium sulfinates in water

S Peng, YX Song, JY He, SS Tang, JX Tan, Z Cao… - Chinese Chemical …, 2019 - Elsevier
An eco-friendly protocol for the synthesis of various 2-sulfonyl quinolines/pyridines through
sulfonylation of heteroaromatic N-oxides with sodium sulfinates in water at ambient …

Phosphonium Salt-Promoted C2–H Functionalization of Heterocyclic N-Oxides

Q Ma, Y Shi, D Wang - Organic Letters, 2023 - ACS Publications
We report the development of a phosphonium salt as a remarkable activating agent that
enables the direct conversion of C2–H bonds of a variety of heterocyclic N-oxides into C2 …

Rh(III)-Catalyzed Regioselective C8-Alkylation of Quinoline N-Oxides with Maleimides and Acrylates

A Thakur, AK Dhiman, Sumit, R Kumar… - The Journal of Organic …, 2021 - ACS Publications
Herein, we disclose the Rh (III)-catalyzed selective C8-alkylation of quinoline N-oxides with
maleimides and acrylates. The main features of the reaction include complete C8-selectivity …

Recent Progress in Non‐Catalytic C–H Functionalization of Heterocyclic N‐Oxides

AV Kutasevich, VP Perevalov… - European Journal of …, 2021 - Wiley Online Library
Considerable attention holds on the chemistry and application of heterocyclic N‐oxides due
to their advantages as building‐blocks in organic synthesis and importance in biomedical …

Transition-metal-and oxidant-free three-component reaction of quinoline N-oxides, sodium metabisulfite and aryldiazonium tetrafluoroborates via a dual radical …

G You, D Xi, J Sun, L Hao, C Xia - Organic & Biomolecular Chemistry, 2019 - pubs.rsc.org
A convenient and straightforward three-component transformation of quinoline N-oxides,
sodium metabisulfite and aryldiazonium tetrafluoroborates has been developed, providing …

Current progress toward synthetic routes and medicinal significance of quinoline

WS Shehab, MMK Amer, DA Elsayed, KK Yadav… - Medicinal Chemistry …, 2023 - Springer
Quinoline motifs are essential in several pharmacological active heterocyclic compounds
due to their various applications in medicinal and industrial chemistry. Furthermore, there …

Quinoline N‐Oxide: A Versatile Precursor in Organic Transformations

K Singha, I Habib, M Hossain - ChemistrySelect, 2022 - Wiley Online Library
Quinoline derivatives are very widely known biologically active heterocyclic compounds, as
for example quinine, mefloquine, etc. In recent years, the interests of researchers are …