Exosomal miRNA-mediated intercellular communications and immunomodulatory effects in tumor microenvironments

HM Nail, CC Chiu, CH Leung, MMM Ahmed… - Journal of biomedical …, 2023 - Springer
Extracellular communication, in other words, crosstalk between cells, has a pivotal role in
the survival of an organism. This communication occurs by different methods, one of which is …

Diabetic retinopathy: Involved cells, biomarkers, and treatments

J Ren, S Zhang, Y Pan, M Jin, J Li, Y Luo… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy (DR), a leading cause of vision loss and blindness worldwide, is
caused by retinal neurovascular unit dysfunction, and its cellular pathology involves at least …

[HTML][HTML] Emerging role of extracellular vesicles in diabetic retinopathy

J Zhu, J Huang, Y Sun, W Xu, H Qian - Theranostics, 2024 - ncbi.nlm.nih.gov
Diabetic retinopathy (DR), a complex complication of diabetes mellitus (DM), is a leading
cause of adult blindness. Hyperglycemia triggers DR, resulting in microvascular damage …

Extracellular vesicles in the retina-putative roles in physiology and disease

AA Kalargyrou, SE Guilfoyle, AJ Smith… - Frontiers in Molecular …, 2023 - frontiersin.org
The retina encompasses a network of neurons, glia and epithelial and vascular endothelia
cells, all coordinating visual function. Traditionally, molecular information exchange in this …

Insight into extracellular vesicles in vascular diseases: intercellular communication role and clinical application potential

W Liu, M Jin, Q Chen, Q Li, X Xing, Y Luo… - Cell Communication and …, 2023 - Springer
Background Cells have been increasingly known to release extracellular vesicles (EVs) to
the extracellular environment under physiological and pathological conditions. A plethora of …

Extracellular vesicles: an emerging player in retinal homeostasis

A Chatterjee, R Singh - Frontiers in Cell and Developmental Biology, 2023 - frontiersin.org
Extracellular vesicles (EVs) encompass secreted membrane vesicles of varied sizes,
including exosomes (− 30–200 nm) and microvesicles (MVs) that are∼ 100–1,000 nm in …

Noncoding RNAs Are Promising Therapeutic Targets for Diabetic Retinopathy: An Updated Review (2017–2022)

M Wang, Q Li, M Jin, Z Wang, X Zhang, X Sun, Y Luo - Biomolecules, 2022 - mdpi.com
Diabetic retinopathy (DR) is the most common complication of diabetes. It is also the main
cause of blindness caused by multicellular damage involving retinal endothelial cells …

The role of aldosterone in the pathogenesis of diabetic retinopathy

K Liu, H Zou, H Fan, H Hu, Y Cheng, J Liu… - Frontiers in …, 2023 - frontiersin.org
Aldosterone, as a mineralocorticoid of adrenal origin, has effects that are not limited to the
urinary tract. As an important regulator in Vasoactive hormone pathways, aldosterone may …

Relationship between Biochemical Pathways and Non-Coding RNAs Involved in the Progression of Diabetic Retinopathy

M Mrowicka, J Mrowicki, I Majsterek - Journal of Clinical Medicine, 2024 - mdpi.com
Diabetic retinopathy (DR) is a progressive blinding disease, which affects the vision and
quality of life of patients, and it severely impacts the society. This complication, caused by …

microRNAs: Critical targets for treating rheumatoid arthritis angiogenesis

L Zhao, Q Wu, Y Long, Q Qu, F Qi, L Liu… - Journal of Drug …, 2024 - Taylor & Francis
Vascular neogenesis, an early event in the development of rheumatoid arthritis (RA)
inflammation, is critical for the formation of synovial vascular networks and plays a key role …