Recompensation in cirrhosis: unravelling the evolving natural history of nonalcoholic fatty liver disease

G Feng, L Valenti, VWS Wong, YM Fouad… - Nature Reviews …, 2024 - nature.com
Recompensation has gained increasing attention in the field of cirrhosis, particularly in
chronic liver disease with a definite aetiology. The current global prevalence of obesity and …

Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH)

X Xu, KL Poulsen, L Wu, S Liu, T Miyata… - Signal transduction and …, 2022 - nature.com
Non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH) has become the leading
cause of liver disease worldwide. NASH, an advanced form of NAFL, can be progressive …

A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement

M Eslam, PN Newsome, SK Sarin, QM Anstee… - Journal of …, 2020 - Elsevier
The exclusion of other chronic liver diseases including “excess” alcohol intake has until now
been necessary to establish a diagnosis of metabolic dysfunction-associated fatty liver …

Comparison of MAFLD and NAFLD diagnostic criteria in real world

SU Lin, J Huang, M Wang, R Kumar, Y Liu… - Liver …, 2020 - Wiley Online Library
Background and aims Metabolic associated fatty liver disease (MAFLD) is a novel concept
proposed in 2020, the utility of which has not been tested and validated in real world. We …

From NASH to HCC: current concepts and future challenges

QM Anstee, HL Reeves, E Kotsiliti, O Govaere… - Nature reviews …, 2019 - nature.com
Caloric excess and sedentary lifestyle have led to a global epidemic of obesity and
metabolic syndrome. The hepatic consequence of metabolic syndrome and obesity …

MAFLD: a consensus-driven proposed nomenclature for metabolic associated fatty liver disease

M Eslam, AJ Sanyal, J George, A Sanyal… - Gastroenterology, 2020 - Elsevier
Fatty liver associated with metabolic dysfunction is common, affects a quarter of the
population, and has no approved drug therapy. Although pharmacotherapies are in …

[HTML][HTML] Alcohol consumption and metabolic syndrome: clinical and epidemiological impact on liver disease

F Åberg, CD Byrne, CJ Pirola, V Männistö… - Journal of …, 2023 - Elsevier
Alcohol use and metabolic syndrome are highly prevalent in the population and frequently
co-exist. Both are implicated in a large range of health problems, including chronic liver …

Differential clinical characteristics and mortality outcomes in persons with NAFLD and/or MAFLD

VH Nguyen, MH Le, RC Cheung, MH Nguyen - Clinical Gastroenterology …, 2021 - Elsevier
Background & aims Metabolic dysfunction–associated fatty liver disease (MAFLD)
establishes new criteria for diagnosing fatty liver disease independent of alcohol intake and …

[PDF][PDF] Report on the AASLD/EASL joint workshop on clinical trial endpoints in NAFLD

ME Rinella, F Tacke, AJ Sanyal, QM Anstee… - …, 2019 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a global public health concern. Its natural history,
the development of nonalcoholic steatohepatitis (NASH) and fibrosis, is highly variable …

Alcoholic liver disease

HK Seitz, R Bataller, H Cortez-Pinto, B Gao… - Nature reviews Disease …, 2018 - nature.com
Alcoholic liver disease (ALD) is the most prevalent type of chronic liver disease worldwide.
ALD can progress from alcoholic fatty liver (AFL) to alcoholic steatohepatitis (ASH), which is …