The impact of ocular blood flow in glaucoma

J Flammer, S Orgül, VP Costa, N Orzalesi… - Progress in retinal and …, 2002 - Elsevier
Two principal theories for the pathogenesis of glaucomatous optic neuropathy (GON) have
been described—a mechanical and a vascular theory. Both have been defended by various …

Inducible rodent models of glaucoma

IH Pang, AF Clark - Progress in retinal and eye research, 2020 - Elsevier
Glaucoma is one of the leading causes of vision impairment worldwide. In order to further
understand the molecular pathobiology of this disease and to develop better therapies …

Regional comparisons of optical coherence tomography angiography vessel density in primary open-angle glaucoma

HL Rao, ZS Pradhan, RN Weinreb, HB Reddy… - American journal of …, 2016 - Elsevier
Purpose To compare the diagnostic abilities of the vessel densities in optic nerve head
(ONH), peripapillary, and macular regions measured using optical coherence tomography …

Risk factors for progression of visual field abnormalities in normal-tension glaucoma

S Drance, DR Anderson, M Schulzer… - American journal of …, 2001 - Elsevier
PURPOSE: To uncover risk factors for the highly variable individual rates of progression in
cases of untreated normal-tension glaucoma. METHODS: Visual field data were assembled …

The blood supply of the optic nerve head and the evaluation of it—myth and reality

SS Hayreh - Progress in retinal and eye research, 2001 - Elsevier
Evidence has gradually emerged that there is vascular insufficiency in the optic nerve head
(ONH) in both anterior ischemic optic neuropathy (AION) and glaucomatous optic …

Nitric oxide: ocular blood flow, glaucoma, and diabetic retinopathy

N Toda, M Nakanishi-Toda - Progress in retinal and eye research, 2007 - Elsevier
Nitric oxide (NO) is widely recognized to be quite an important intercellular messenger in the
cardiovascular and nervous systems or immunological reactions, including that in the eye …

Retinal vessel diameter and open-angle glaucoma: the Blue Mountains Eye Study

P Mitchell, H Leung, JJ Wang, E Rochtchina, AJ Lee… - Ophthalmology, 2005 - Elsevier
PURPOSE: To examine the relationship between open-angle glaucoma (OAG) and retinal
vessel diameter among baseline participants in the Blue Mountains Eye Study. DESIGN …

The pharmacology of nitric oxide in the peripheral nervous system of blood vessels

N Toda, T Okamura - Pharmacological reviews, 2003 - ASPET
Unanticipated, novel hypothesis on nitric oxide (NO) radical, an inorganic, labile, gaseous
molecule, as a neurotransmitter first appeared in late 1989 and into the early 1990s, and …

Retinal vasculature in glaucoma: a review

KKW Chan, F Tang, CCY Tham, AL Young… - BMJ open …, 2017 - bmjophth.bmj.com
Despite the critical impact of glaucoma on global blindness, its aetiology is not fully
characterised. Elevated intraocular pressure is highly associated with glaucomatous optic …

Ocular hemodynamics and glaucoma prognosis: a color Doppler imaging study

F Galassi, A Sodi, F Ucci, G Renieri… - Archives of …, 2003 - jamanetwork.com
Objective To evaluate the effect of optic nerve circulation, using color Doppler imaging (CDI),
on the progression of visual field damage in primary open-angle glaucoma. Methods The …