Emerging treatment strategies in wound care

M Mirhaj, S Labbaf, M Tavakoli… - International Wound …, 2022 - Wiley Online Library
Wound healing is a complex process in tissue regeneration through which the body
responds to the dissipated cells as a result of any kind of severe injury. Diabetic and non …

[HTML][HTML] Systematic review: adipose-derived mesenchymal stem cells, platelet-rich plasma and biomaterials as new regenerative strategies in chronic skin wounds …

P Gentile, S Garcovich - International Journal of Molecular Sciences, 2021 - mdpi.com
The number of clinical trials evaluating adipose-derived mesenchymal stem cells (AD-
MSCs), platelet-rich plasma (PRP), and biomaterials efficacy in regenerative plastic surgery …

[HTML][HTML] Human adipose-derived mesenchymal stem cells-derived exosomes encapsulated in pluronic F127 hydrogel promote wound healing and regeneration

Y Zhou, XL Zhang, ST Lu, NY Zhang, HJ Zhang… - Stem cell research & …, 2022 - Springer
Background Large area skin trauma has always been a great challenge for both patients
and clinicians. Exosomes originating from human adipose-derived mesenchymal stem cells …

[HTML][HTML] Optimization of mesenchymal stromal cell (MSC) manufacturing processes for a better therapeutic outcome

ME Fernández-Santos, M Garcia-Arranz… - Frontiers in …, 2022 - frontiersin.org
MSCs products as well as their derived extracellular vesicles, are currently being explored
as advanced biologics in cell-based therapies with high expectations for their clinical use in …

[HTML][HTML] Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway

N Ebrahim, AA Dessouky, O Mostafa… - Stem cell research & …, 2021 - Springer
Background Diabetic foot ulceration is a serious chronic complication of diabetes mellitus
characterized by high disability, mortality, and morbidity. Platelet-rich plasma (PRP) has …

[HTML][HTML] Systematic review: Advances of fat tissue engineering as bioactive scaffold, bioactive material, and source for adipose-derived mesenchymal stem cells in …

P Gentile, A Sterodimas, C Calabrese… - Stem cell research & …, 2021 - Springer
Fat tissue (FT) has been used for many years in regenerative surgery as a bioactive material
through the lipofilling/fat graft (F-GRF)–nano-fat technique, as a bioactive scaffold when it …

Adipose-derived stromal stem cells (ASCs) as a new regenerative immediate therapy combating coronavirus (COVID-19)-induced pneumonia

P Gentile, A Sterodimas - Expert opinion on biological therapy, 2020 - Taylor & Francis
A recent investigation published by Leng et al.[1], reported exceptional outcomes in
improved pulmonary functional activity, into seven patients who suffered Coronavirus …

[HTML][HTML] Adipose stem cells (ASCs) and stromal vascular fraction (SVF) as a potential therapy in combating (COVID-19)-disease

P Gentile, A Sterodimas - Aging and disease, 2020 - ncbi.nlm.nih.gov
A recent and interesting study reported improved respiratory activity after intravenous
administration of mesenchymal stem cells (MSCs) into patients affected by coronavirus …

[HTML][HTML] Safety and efficacy of mesenchymal stem cells in severe/critical patients with COVID-19: A systematic review and meta-analysis

W Yao, H Dong, J Qi, Y Zhang, L Shi - EClinicalMedicine, 2022 - thelancet.com
Background The present study aims to better understand the efficacy and safety of
mesenchymal stromal cells (MSCs) in treating severe/critical patients with COVID-19 …

[HTML][HTML] Adipose-derived mesenchymal stem cells (AD-MSCs) against ultraviolet (UV) radiation effects and the skin photoaging

P Gentile, S Garcovich - Biomedicines, 2021 - mdpi.com
The skin is a natural barrier against the ultraviolet (UV) radiation of sunlight. The long-term
and/or repetitive exposure to the sunlight and related UV radiation may change the skin …