Laminins

M Durbeej - Cell and tissue research, 2010 - Springer
Laminins are cell adhesion molecules that comprise a family of glycoproteins found
predominantly in basement membranes, which are the thin sheets of extracellular matrix that …

The endothelial cell tube formation assay on basement membrane turns 20: state of the science and the art

I Arnaoutova, J George, HK Kleinman, G Benton - Angiogenesis, 2009 - Springer
It has been more than 20 years since it was first demonstrated that endothelial cells will
rapidly form capillary-like structures in vitro when plated on top of a reconstituted basement …

Syndecans as receptors and organizers of the extracellular matrix

X Xian, S Gopal, JR Couchman - Cell and tissue research, 2010 - Springer
Syndecans are type I transmembrane proteins having a core protein modified with
glycosaminoglycan chains, most commonly heparan sulphate. They are an ancient group of …

[HTML][HTML] Myofibroblasts and the extracellular matrix network in post-myocardial infarction cardiac remodeling

Y Ma, LE de Castro Brás, H Toba, RP Iyer… - … -European Journal of …, 2014 - Springer
The cardiac extracellular matrix (ECM) fills the space between cells, supports tissue
organization, and transduces mechanical, chemical, and biological signals to regulate …

Laminin-211 in skeletal muscle function

J Holmberg, M Durbeej - Cell adhesion & migration, 2013 - Taylor & Francis
A chain is no stronger than its weakest link is an old idiom that holds true for muscle biology.
As the name implies, skeletal muscle's main function is to move the bones. However, for a …

Extracellular matrix roles during cardiac repair

C Jourdan-LeSaux, J Zhang, ML Lindsey - Life sciences, 2010 - Elsevier
The cardiac extracellular matrix (ECM) provides a platform for cells to maintain structure and
function, which in turn maintains tissue function. In response to injury, the ECM undergoes …

[HTML][HTML] Skeletal muscle laminin and MDC1A: pathogenesis and treatment strategies

KI Gawlik, M Durbeej - Skeletal muscle, 2011 - Springer
Laminin-211 is a cell-adhesion molecule that is strongly expressed in the basement
membrane of skeletal muscle. By binding to the cell surface receptors dystroglycan and …

Laminin-inspired cell-instructive microenvironments for neural stem cells

D Barros, IF Amaral, AP Pego - Biomacromolecules, 2019 - ACS Publications
Laminin is a heterotrimeric glycoprotein with a key role in the formation and maintenance of
the basement membrane architecture and properties, as well as on the modulation of …

The role of laminins in the organization and function of neuromuscular junctions

RS Rogers, H Nishimune - Matrix Biology, 2017 - Elsevier
The synapse between motor neurons and skeletal muscle is known as the neuromuscular
junction (NMJ). Proper alignment of presynaptic and post-synaptic structures of motor …

Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins

TJ Rowland, AJ Blaschke, DE Buchholz… - Journal of tissue …, 2013 - Wiley Online Library
A potential application of human embryonic stem cells (hESCs) and induced pluripotent
stem cells (iPSCs) is the generation of retinal pigmented epithelium (RPE) to treat age …