[HTML][HTML] Inflammation and aging: signaling pathways and intervention therapies
Aging is characterized by systemic chronic inflammation, which is accompanied by cellular
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
senescence, immunosenescence, organ dysfunction, and age-related diseases. Given the …
[HTML][HTML] Inflammasome activation at the crux of severe COVID-19
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly …
(SARS-CoV-2), results in life-threatening disease in a minority of patients, especially elderly …
Pathogenesis of pneumonia and acute lung injury
ME Long, RK Mallampalli, JC Horowitz - Clinical Science, 2022 - portlandpress.com
Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary
and critical care healthcare professionals, and these challenges have recently garnered …
and critical care healthcare professionals, and these challenges have recently garnered …
[HTML][HTML] Diversity and complexity of cell death: a historical review
Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …
[HTML][HTML] NETosis and neutrophil extracellular traps in COVID-19: immunothrombosis and beyond
Y Zhu, X Chen, X Liu - Frontiers in Immunology, 2022 - frontiersin.org
Infection with SARS-CoV-2, the causative agent of the Coronavirus disease 2019 (COVID-
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
19) pandemic, causes respiratory problems and multifaceted organ dysfunction. A crucial …
Neutrophil intrinsic and extrinsic regulation of NETosis in health and disease
Neutrophil extracellular traps (NETs) evolved to protect the host against microbial infections
and are formed by a web-like structure of DNA that is decorated with antimicrobial effectors …
and are formed by a web-like structure of DNA that is decorated with antimicrobial effectors …
Inflammation, infection and venous thromboembolism
ME Colling, BE Tourdot, Y Kanthi - Circulation research, 2021 - Am Heart Assoc
The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …
recognized; yet, only in the last decades have we begun to understand the mechanisms …
[HTML][HTML] Neutrophils in COVID-19: not innocent bystanders
E McKenna, R Wubben, JM Isaza-Correa… - Frontiers in …, 2022 - frontiersin.org
Unusually for a viral infection, the immunological phenotype of severe COVID-19 is
characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil …
characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil …
[HTML][HTML] Putative origins of cell-free DNA in humans: a review of active and passive nucleic acid release mechanisms
S Grabuschnig, AJ Bronkhorst, S Holdenrieder… - International journal of …, 2020 - mdpi.com
Through various pathways of cell death, degradation, and regulated extrusion, partial or
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …
complete genomes of various origins (eg, host cells, fetal cells, and infiltrating viruses and …
[HTML][HTML] Receptor-mediated NETosis on neutrophils
T Chen, Y Li, R Sun, H Hu, Y Liu, M Herrmann… - Frontiers in …, 2021 - frontiersin.org
Neutrophil extracellular traps (NETs), a web-like structures containing chromatin, have a
significant role in assisting the capture and killing of microorganisms by neutrophils during …
significant role in assisting the capture and killing of microorganisms by neutrophils during …