The use of patient-derived dendritic cells (DCs) as a means to elicit therapeutically relevant
immune responses in cancer patients has been extensively investigated throughout the past …

Concerted efforts of tumor immunologists over more than two decades contributed
numerous well-defined tumor antigens, many of which were promptly developed into cancer …

Common 'themes' in epidemiology related to cancer risk beg a comprehensive mechanistic
explanation. As people age, risk for cancer increases. Obesity and smoking increase the risk …

Tumour‐associated autoantibodies may be promising biomarkers that could facilitate breast
cancer (BC) diagnosis and improve patient outcomes. This review aims to identify the …

Abstract Cyclin B1 (CCNB1) is considered as a potential target for a cancer vaccine, as it is
overexpressed in many malignant cells, while being transiently expressed in normal cells …

Ex vivo expanded tumor infiltrating lymphocytes (TILs) from malignant melanoma (MM) and
head & neck squamous cell carcinoma (HNSCC) share a similar oligoclonal composition of …

Cyclin B1 is a checkpoint protein that regulates cell division from G2 to the M phase. Studies
in mice have shown that cyclin B1 vaccine-induced immunity significantly delayed or …

Continuous cell division is a hallmark of cancer and cell-cycle regulators therefore represent
relevant target molecules for tumor therapy. Among these targets the cyclins are of particular …

Cyclin A1-derived peptides recently gained new interest in a study by Ochsenreither et al.,
who characterized cyclin A1 as a promising antigen in acute myeloid leukemia (AML) due to …

Die meisten malignen Erkrankungen treten mit zunehmendem Alter jenseits des 50.
Lebensjahres auf. Die Genese für jede einzelne maligne Erkrankung ist in der Regel nicht …