Directed evolution: methodologies and applications

Y Wang, P Xue, M Cao, T Yu, ST Lane… - Chemical reviews, 2021 - ACS Publications
Directed evolution aims to expedite the natural evolution process of biological molecules
and systems in a test tube through iterative rounds of gene diversifications and library …

Recent advances in droplet microfluidics for single-cell analysis

Z Jiang, H Shi, X Tang, J Qin - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
Single-cell manipulation and analysis is essential for studying many fundamental biological
processes and discovering cellular heterogeneity. Multi-parameter studies of intercellular …

Ultrahigh-Throughput Enzyme Engineering and Discovery in In Vitro Compartments

M Gantz, S Neun, EJ Medcalf, LD van Vliet… - Chemical …, 2023 - ACS Publications
Novel and improved biocatalysts are increasingly sourced from libraries via experimental
screening. The success of such campaigns is crucially dependent on the number of …

Multiphase chemistry under nanoconfinement: An electrochemical perspective

SM Lu, KJ Vannoy, JE Dick… - Journal of the American …, 2023 - ACS Publications
Most relevant systems of interest to modern chemists rarely consist of a single phase. Real-
world problems that require a rigorous understanding of chemical reactivity in multiple …

Integration of microfluidic channel on electrochemical-based nanobiosensors for monoplex and multiplex analyses: an overview

H Adam, SCB Gopinath, MKM Arshad, T Adam… - Journal of the Taiwan …, 2023 - Elsevier
Background Microfluidic devices have evolved into low-cost, simple, and powerful analytical
tool platforms. Herein, an electrochemically-based microfluidic nanobiosensor array for …

Micro‐Droplets Parameters Monitoring in a Microfluidic Chip via Liquid‐Solid Triboelectric Nanogenerator

W Liu, H Li, Q Gao, D Zhao, Y Yu, Q Xiang… - Advanced …, 2023 - Wiley Online Library
The monitoring of micro‐droplets parameters is significant to the development of droplet
microfluidics. However, existing monitoring methods have drawbacks such as high cost …

UV–Vis spectra-activated droplet sorting for label-free chemical identification and collection of droplets

TA Duncombe, A Ponti, FP Seebeck… - Analytical …, 2021 - ACS Publications
We introduce the UV–vis spectra-activated droplet sorter (UVADS) for high-throughput label-
free chemical identification and enzyme screening. In contrast to previous absorbance …

Microfluidics for peptidomics, proteomics, and cell analysis

R Vitorino, S Guedes, JP da Costa, V Kašička - Nanomaterials, 2021 - mdpi.com
Microfluidics is the advanced microtechnology of fluid manipulation in channels with at least
one dimension in the range of 1–100 microns. Microfluidic technology offers a growing …

[HTML][HTML] Advantages of optical fibers for facile and enhanced detection in droplet microfluidics

S Hengoju, O Shvydkiv, M Tovar, M Roth… - Biosensors and …, 2022 - Elsevier
Droplet microfluidics offers a unique opportunity for ultrahigh-throughput experimentation
with minimal sample consumption and thus has obtained increasing attention, particularly …

Multiplex detection of infectious diseases on microfluidic platforms

F Chen, Q Hu, H Li, Y Xie, L Xiu, Y Zhang, X Guo, K Yin - Biosensors, 2023 - mdpi.com
Infectious diseases contribute significantly to the global disease burden. Sensitive and
accurate screening methods are some of the most effective means of identifying sources of …