Multiple dysregulated signaling pathways are implicated in the pathogenesis of cancer. The
conventional therapies used in cancer prevention/treatment suffer from low efficacy …

Acute myeloid leukemia (AML) is a hematological malignancy characterized by uncontrolled
proliferation, differentiation arrest, and accumulation of immature myeloid progenitors …

Acute myeloid leukemia (AML) is a highly heterogeneous hematopoietic malignancy
characterized by excessive proliferation and accumulation of immature myeloid blasts in the …

Acute myeloid leukemia (AML) is the most common acute leukemia in adults that affects the
myeloid lineage. The recent advances have upgraded our understanding of the cytogenetic …

Small-molecule subcellular organelle-targeting theranostic probes are crucial for early
disease diagnosis and treatment. The imaging window of these molecules is mainly focused …

Natural products that contain ortho-quinones show great potential as anticancer agents but
have been largely discarded from clinical development because their redox-cycling …

Acute myeloid leukemia (AML) is a heterogeneous disease caused by several gene
mutations and cytogenetic abnormalities affecting differentiation and proliferation of myeloid …

Immune surveillance mechanisms comprising of adaptive and innate immune systems are
naturally designed to eliminate AML development. However, leukemic cells apply various …

The inflammatory response is known to have a significant role in certain autoimmune
diseases and malignancies. We review current knowledge regarding the functions of …

Background Acute myeloid leukemia (AML) is a heterogenous malignancy driven by genetic
and epigenetic factors. Inhibition of bromodomain and extraterminal (BET) proteins …