Abstract Recently, United States Food and Drug Administration (FDA) and European
Commission (EC) approved Alnylam Pharmaceuticals' RNA interference (RNAi) therapeutic …

RNA interference (RNAi) is a natural process through which expression of a targeted gene
can be knocked down with high specificity and selectivity. Using available technology and …

Through a mechanism known as RNA interference (RNAi), small interfering RNA (siRNA)
molecules can target complementary mRNA strands for degradation, thus specifically …

Short interfering RNAs can be used to silence gene expression in a sequence-specific
manner in a process that is known as RNA interference. The application of RNA interference …

The discovery of RNA interference (RNAi) may well be one of the transforming events in
biology in the past decade. RNAi can result in gene silencing or even in the expulsion of …

We show that human adenovirus inhibits RNA interference (RNAi) at late times of infection
by suppressing the activity of two key enzyme systems involved, Dicer and RNA-induced …

The present invention provides methods of enhancing the e? icacy and speci? city of RNAi.
The invention also provides compositions for mediating RNAi. In particular, the invention …

For reversal of MDR1 gene-dependent multidrug resistance (MDR), two small interfering
RNA (siRNA) constructs were designed to inhibit MDR1 expression by RNA interference …

Antisense oligonucleotides are molecules that are able to inhibit gene expression being,
therefore, potentially active for the treatment of viral infections cancer or inflammatory …

There are mainly two types of short RNAs that target complementary messengers in animals:
small interfering RNAs and micro-RNAs. Both are produced by the cleavage of double …