Diagnosis and prediction of CKD progression by assessment of urinary peptides

JP Schanstra, P Zürbig, A Alkhalaf… - Journal of the …, 2015 - journals.lww.com
Progressive CKD is generally detected at a late stage by a sustained decline in eGFR and/or
the presence of significant albuminuria. With the aim of early and improved risk stratification …

Urinary proteomics in the assessment of chronic kidney disease

W Mullen, C Delles, H Mischak - Current Opinion in Nephrology …, 2011 - journals.lww.com
Urinary proteomic biomarkers have emerged as clinically relevant variables. First studies
involving several hundred individuals indicate a potential added benefit of urinary proteomic …

Implementation of proteomic biomarkers: making it work

H Mischak, JPA Ioannidis, A Argiles… - European journal of …, 2012 - Wiley Online Library
Eur J Clin Invest 2012; 42 (9): 1027–1036 Abstract While large numbers of proteomic
biomarkers have been described, they are generally not implemented in medical practice …

Integrative biology identifies shared transcriptional networks in CKD

S Martini, V Nair, BJ Keller, F Eichinger… - Journal of the …, 2014 - journals.lww.com
A previous meta-analysis of genome-wide association data by the Cohorts for Heart and
Aging Research in Genomic Epidemiology and CKDGen consortia identified 16 loci …

Proteomics and metabolomics in renal transplantation‐quo vadis?

R Bohra, J Klepacki, J Klawitter, J Klawitter… - Transplant …, 2013 - Wiley Online Library
The improvement of long‐term transplant organ and patient survival remains a critical
challenge following kidney transplantation. Proteomics and biochemical profiling …

[HTML][HTML] Circulating renalase predicts all-cause mortality and renal outcomes in patients with advanced chronic kidney disease

SH Baek, R Cha, SW Kang, CW Park… - The Korean journal of …, 2019 - ncbi.nlm.nih.gov
Methods A retrospective analysis of the K-STAR data was performed including 383 patients
with CKD (mean age, 56.4 years; male/female, 252/131). We measured circulating renalase …

State-of-the-art non-targeted metabolomics in the study of chronic kidney disease

J Boelaert, R t'Kindt, E Schepers, L Jorge, G Glorieux… - Metabolomics, 2014 - Springer
Here we report a metabolomics discovery study conducted on blood serum samples of
patients in different stages of chronic kidney disease (CKD). Metabolites were monitored on …

Urinary peptide biomarker panel associated with an improvement in estimated glomerular filtration rate in chronic kidney disease patients

K Markoska, M Pejchinovski, C Pontillo… - Nephrology Dialysis …, 2018 - academic.oup.com
Background An improvement in the glomerular filtration rate (GFR) of chronic kidney disease
patients has been an underestimated clinical outcome. Although this may be considered as …

Application of Machine Learning in Chronic Kidney Disease: Current Status and Future Prospects

C Delrue, S De Bruyne, MM Speeckaert - Biomedicines, 2024 - mdpi.com
The emergence of artificial intelligence and machine learning (ML) has revolutionized the
landscape of clinical medicine, offering opportunities to improve medical practice and …

A systematic review and participant-level meta-analysis found little association of retinal microvascular caliber with reduced kidney function

WK Lye, E Paterson, CC Patterson, AP Maxwell… - Kidney international, 2021 - Elsevier
Previously, variation in retinal vascular caliber has been reported in association with chronic
kidney disease (CKD) but findings remain inconsistent. To help clarify this we conducted …