Fibrotic pathways and fibroblast-like synoviocyte phenotypes in osteoarthritis
A Damerau, E Rosenow, D Alkhoury… - Frontiers in …, 2024 - frontiersin.org
Osteoarthritis (OA) is the most common form of arthritis, characterized by osteophyte
formation, cartilage degradation, and structural and cellular alterations of the synovial …
formation, cartilage degradation, and structural and cellular alterations of the synovial …
[HTML][HTML] Mitochondrial-oriented injectable hydrogel microspheres maintain homeostasis of chondrocyte metabolism to promote subcellular therapy in osteoarthritis
Subcellular mitochondria serve as sensors for energy metabolism and redox balance, and
the dynamic regulation of functional and dysfunctional mitochondria plays a crucial role in …
the dynamic regulation of functional and dysfunctional mitochondria plays a crucial role in …
[HTML][HTML] New trends in osteoarthritis treatment
Osteoarthritis (OA) is the most common type of arthritis affecting millions of persons
worldwide (1, 2). It is a complex and multifactorial disease that could affect any joint, but …
worldwide (1, 2). It is a complex and multifactorial disease that could affect any joint, but …
Mitoregulin modulates inflammation in osteoarthritis: Insights from synovial transcriptomics and cellular studies
M Choi, JS Min, SW Moon, J Jeon, HK Do… - … and Biophysical Research …, 2024 - Elsevier
Osteoarthritis is a prevalent musculoskeletal disease that involves cartilage degradation,
subchondral bone remodeling, and synovial inflammation and ultimately causes physical …
subchondral bone remodeling, and synovial inflammation and ultimately causes physical …
Oxidative stress in patients with osteoarthritis with infectious urinary tract: Approach through gene network analysis, urinary myeloperoxidase activity, and the oxidant …
İ Demirhan, E Öner, EB Kurutas - Indian Journal of Experimental …, 2024 - or.niscpr.res.in
Determining MPO activity and oxidant/antioxidant (MDA, SOD and CAT) levels in the urine of
osteoarthritis patients with urinary infection was also performed for the first time to reveal the …
osteoarthritis patients with urinary infection was also performed for the first time to reveal the …
Synovial fluid transcriptome dynamics in osteoarthritis progression: Implications in pathogenesis
R Sharma, D Rana, R Kumar, S Narula, A Chaudhary… - bioRxiv, 2024 - biorxiv.org
Background: Osteoarthritis, a degenerative joint disease associated with various
pathological manifestations in the joint including cartilage loss, alterations in subchondral …
pathological manifestations in the joint including cartilage loss, alterations in subchondral …
Mechanical overloading induces chondrocyte apoptosis via lysosomal acidification loss and TRPML1 hyperactivation
H Yao, HS Ooi, Y Lan, C Yi, Y Su - 2024 - researchsquare.com
Mechanical overload induces chondrocyte apoptosis in post-traumatic arthritis (PTA),
associated with dysregulation of calcium signaling. However, the role of lysosomal calcium …
associated with dysregulation of calcium signaling. However, the role of lysosomal calcium …