The benzene moiety is the most prevalent ring system in marketed drugs, underscoring its
historic popularity in drug design either as a pharmacophore or as a scaffold that projects …

Monoterpenes, comprising hydrocarbons, are the largest class of plant secondary
metabolites and are commonly found in essential oils. Monoterpenes and their derivatives …

AD is a progressive neurodegenerative disorder and a leading cause of dementia in an
aging population worldwide. The enormous challenge which AD possesses to global …

The formation of carbon–nitrogen bonds for the preparation of aromatic amines is among the
top five reactions carried out globally for the production of high-value materials, ranging from …

Polycyclic polyprenylated acylphloroglucinols (PPAPs) are a class of hybrid natural products
sharing the mevalonate/methylerythritol phosphate and polyketide biosynthetic pathways …

A visible-light-induced decarboxylation reaction was developed for the synthesis of alkylated
benzimidazo [2, 1-a] isoquinoline-6 (5 H)-ones and indolo [2, 1-a] isoquinolin-6 (5 H)-ones …

Numerous variations on structural motifs exist within pharmaceutical compounds that have
entered the clinic. These variations have amounted over many decades based on years of …

The replacement of one chemical motif with another that is broadly similar is a common
method in medicinal chemistry to modulate the physical and biological properties of a …

A simple and efficient decarboxylative radical addition/cyclization strategy was developed,
by which a wide range of benzimidazo [2, 1-a] isoquinoline-6 (5H)-ones were prepared in …

The adamantane moiety is widely applied in design and synthesis of new drug delivery
systems and in surface recognition studies. This review focuses on liposomes, cyclodextrins …