Mitochondria are known to generate approximately 90% of cellular reactive oxygen species
(ROS). The imbalance between mitochondrial reactive oxygen species (mtROS) production …

The diagnostic criteria published by the PNS (Paraneoplastic Neurological Syndromes)
Euronetwork in 2004 provided a useful classification of PNS, including paraneoplastic …

Background Amyloid light-chain (AL) amyloidosis is an ultra-rare disease associated with
significant morbidity and mortality. Few studies have examined the global epidemiology of …

Background Amyloidosis is a complex group of rare conditions. For patients, amyloidosis is
severely debilitating: physically and psychologically. Currently, data are lacking to evaluate …

Amyloidosis refers to an etiologically heterogeneous group of protein misfolding diseases,
pathologically characterized by extracellular amyloid fibrils producing congophillic …

Amyloidosis refers to a group of conditions where abnormal protein—or amyloid—deposits
in tissues or organs, often leading to organ malfunction. Amyloidosis affects nearly any …

Amyloidosis can involve the gastrointestinal (GI) tract, and deposition can present with
varied histologic patterns that make recognition challenging. This retrospective …

AL amyloidosis is caused by the misfolding of immunoglobulin light chains leading to an
impaired function of tissues and organs in which they accumulate. Due to the paucity of …

Background Amyloid light chain (AL) amyloidosis is the most common systemic amyloidosis.
The objective of this scoping review was to map the available literature on the diagnosis of …

Monoclonal gammopathies (MG) encompass a variety of disorders related to clonal
expansion and/or malignant transformation of B lymphocytes. Deposition of free …