Purpose of the Review To provide an up-to-date review of the incidence of stroke and large
vessel occlusion (LVO) around the globe, as well as the eligibility and access to IV …

Background and Purpose—Estimates of risk of stroke recurrence are widely variable and
focused on the short-term. A systematic review and meta-analysis was conducted to …

Background Diagnostic errors cause substantial preventable harms worldwide, but rigorous
estimates for total burden are lacking. We previously estimated diagnostic error and serious …

Objectives: Efficacy of thrombolytic therapy for ischemic stroke decreases with time elapsed
from symptom onset. We analyzed the effect of interventions aimed to reduce treatment …

Thrombolysis with alteplase administered within a narrow therapeutic window provides an
effective therapy for acute ischaemic stroke. However, mainly because of prehospital delay …

In acute stroke management, time is brain. Bringing swift treatment to the patient, instead of
the conventional approach of awaiting the patient's arrival at the hospital for treatment, is a …

Esta edição traz as Diretrizes Brasileiras sobre o Manejo da Ressuscitação Cardiopulmonar
(RCP). Embora a ressuscitação tenha uma longa história que remonta aos tempos bíblicos …

Among the high prevalence of cerebrovascular diseases nowadays, acute ischemic stroke
stands out, representing a significant worldwide health issue with important socio-economic …

Background and Purpose—The benefit of intravenous thrombolytic therapy in acute brain
ischemia is strongly time dependent. Methods—The Get With the Guidelines–Stroke …

Despite the availability of thrombolytic and endovascular therapy for acute ischemic stroke,
many patients are ineligible due to delayed hospital arrival. The identification of factors …