Physiological roles of hydrogen sulfide in mammalian cells, tissues, and organs

G Cirino, C Szabo… - Physiological …, 2023 - journals.physiology.org
Over the last two decades, hydrogen sulfide (H2S) has emerged as an endogenous
regulator of a broad range of physiological functions. H2S belongs to the class of molecules …

Neural stem cell therapy for subacute and chronic ischemic stroke

AC Boese, QSE Le, D Pham, MH Hamblin… - Stem cell research & …, 2018 - Springer
Neural stem cells (NSCs) play vital roles in brain homeostasis and exhibit a broad repertoire
of potentially therapeutic actions following neurovascular injury. One such injury is stroke, a …

Alzheimer's disease as a synaptopathy: Evidence for dysfunction of synapses during disease progression

S Meftah, J Gan - Frontiers in Synaptic Neuroscience, 2023 - frontiersin.org
The synapse has consistently been considered a vulnerable and critical target within
Alzheimer's disease, and synapse loss is, to date, one of the main biological correlates of …

Genetic variations influence brain changes in patients with attention-deficit hyperactivity disorder

SK Yadav, AA Bhat, S Hashem, S Nisar… - Translational …, 2021 - nature.com
Attention-deficit hyperactivity disorder (ADHD) is a neurological and neurodevelopmental
childhood-onset disorder characterized by a persistent pattern of inattentiveness …

[HTML][HTML] Vascular cognitive impairment–Past, present, and future challenges

A Badji, J Youwakim, A Cooper, E Westman… - Ageing Research …, 2023 - Elsevier
Vascular cognitive impairment (VCI) is a lifelong process encompassing a broad spectrum of
cognitive disorders, ranging from subtle or mild deficits to prodromal and fully developed …

Blood–brain barrier disruption, vascular impairment, and ischemia/reperfusion damage in diabetic stroke

P Venkat, M Chopp, J Chen - Journal of the American Heart …, 2017 - Am Heart Assoc
Stroke is a major cause of death and long-term disability accompanied by steep social and
medical costs. Diabetes mellitus (DM) is a chronic, lifelong, severe metabolic health problem …

Mechanism of depression as a risk factor in the development of Alzheimer's disease: the function of AQP4 and the glymphatic system

M Xia, L Yang, G Sun, S Qi, B Li - Psychopharmacology, 2017 - Springer
Background Many studies have indicated that a history of depression increases the risk of
developing Alzheimer's disease (AD); however, the potential pathogenestic mechanism by …

Altered coupling between resting-state cerebral blood flow and functional connectivity in schizophrenia

J Zhu, C Zhuo, L Xu, F Liu, W Qin, C Yu - Schizophrenia Bulletin, 2017 - academic.oup.com
Background Respective changes in resting-state cerebral blood flow (CBF) and functional
connectivity in schizophrenia have been reported. However, their coupling alterations in …

Cerebral perfusion changes in post-concussion syndrome: a prospective controlled cohort study

KM Barlow, LD Marcil, D Dewey, HL Carlson… - Journal of …, 2017 - liebertpub.com
The biology of post-concussive symptoms is unclear. Symptoms are often increased during
activities, and have been linked to decreased cerebrovascular reactivity and perfusion. The …

Cerebral microcirculation, perivascular unit, and glymphatic system: role of aquaporin-4 as the gatekeeper for water homeostasis

J Szczygielski, M Kopańska, A Wysocka… - Frontiers in …, 2021 - frontiersin.org
In the past, water homeostasis of the brain was understood as a certain quantitative
equilibrium of water content between intravascular, interstitial, and intracellular spaces …