COVID-19 complications: oxidative stress, inflammation, and mitochondrial and endothelial dysfunction

E Georgieva, J Ananiev, Y Yovchev… - International Journal of …, 2023 - mdpi.com
SARS-CoV-2 infection, discovered and isolated in Wuhan City, Hubei Province, China,
causes acute atypical respiratory symptoms and has led to profound changes in our lives …

COVID-19 and acute kidney injury

J Hilton, N Boyer, MK Nadim, LG Forni… - Critical Care …, 2022 - criticalcare.theclinics.com
In December 2019, a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
was discovered in Wuhan, China, the rapid spread of which culminated in a global …

Targeting immunometabolism against acute lung injury

L Ning, Z Shishi, W Bo, L Huiqing - Clinical Immunology, 2023 - Elsevier
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening
conditions triggered by multiple intra-and extra-pulmonary injury factors, characterized by …

Evaluation of inhaled nitric oxide (iNO) treatment for moderate-to-severe ARDS in critically ill patients with COVID-19: a multicenter cohort study

K Al Sulaiman, GB Korayem, AF Altebainawi… - Critical Care, 2022 - Springer
Background Inhaled nitric oxide (iNO) is used as rescue therapy in patients with refractory
hypoxemia due to severe COVID-19 acute respiratory distress syndrome (ARDS) despite the …

Non-coding RNAs expression in SARS-CoV-2 infection: pathogenesis, clinical significance, and therapeutic targets

X Liu, W Xiong, M Ye, T Lu, K Yuan, S Chang… - … and Targeted Therapy, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has been looming globally for
three years, yet the diagnostic and treatment methods for COVID-19 are still undergoing …

Advances in the regulation of macrophage polarization by mesenchymal stem cells and implications for ALI/ARDS treatment

C Liu, K Xiao, L Xie - Frontiers in Immunology, 2022 - frontiersin.org
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a common condition
with high mortality. ALI/ARDS is caused by multiple etiologies, and the main clinical …

COVID-19 and neurological manifestations

K Forero, R Buqaileh, C Sunderman, W AbouAlaiwi - Brain Sciences, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a newly emerged
coronavirus, has sparked a global pandemic with its airborne transmission and ability to …

Acute respiratory distress syndrome; a review of recent updates and a glance into the future

HF Ramji, M Hafiz, HH Altaq, ST Hussain, F Chaudry - Diagnostics, 2023 - mdpi.com
Acute respiratory distress syndrome (ARDS) is a rapidly progressive form of respiratory
failure that accounts for 10% of admissions to the ICU and is associated with approximately …

Pulmonary drug delivery for acute respiratory distress syndrome

Q Fei, I Bentley, SN Ghadiali, JA Englert - Pulmonary Pharmacology & …, 2023 - Elsevier
The acute respiratory distress syndrome (ARDS) is a life-threatening condition that causes
respiratory failure. Despite numerous clinical trials, there are no molecularly targeted …

Role of toll-like receptors and nod-like receptors in acute lung infection

J Le, Y Kulatheepan, S Jeyaseelan - Frontiers in Immunology, 2023 - frontiersin.org
The respiratory system exposed to microorganisms continuously, and the pathogenicity of
these microbes not only contingent on their virulence factors, but also the host's immunity. A …