[HTML][HTML] Black phosphorus, an emerging versatile nanoplatform for cancer immunotherapy

H Liu, Y Mei, Q Zhao, A Zhang, L Tang, H Gao… - Pharmaceutics, 2021 - mdpi.com
Black phosphorus (BP) is one of the emerging versatile nanomaterials with outstanding
biocompatibility and biodegradability, exhibiting great potential as a promising inorganic …

[HTML][HTML] Kickstarting immunity in cold tumours: localised tumour therapy combinations with immune checkpoint blockade

E Appleton, J Hassan, C Chan Wah Hak… - Frontiers in …, 2021 - frontiersin.org
Cancer patients with low or absent pre-existing anti-tumour immunity (“cold” tumours)
respond poorly to treatment with immune checkpoint inhibitors (ICPI). In order to render …

[HTML][HTML] Current prospects for treatment of solid tumors via photodynamic, photothermal, or ionizing radiation therapies combined with immune checkpoint inhibition (a …

S Anand, TA Chan, T Hasan, EV Maytin - Pharmaceuticals, 2021 - mdpi.com
Photodynamic therapy (PDT) causes selective damage to tumor cells and vasculature and
also triggers an anti-tumor immune response. The latter fact has prompted the exploration of …

[HTML][HTML] Recent advances in nanoparticles-based photothermal therapy synergizing with immune checkpoint blockade therapy

X Dai, X Li, Y Liu, F Yan - Materials & Design, 2022 - Elsevier
Several breakthroughs have been achieved in anti-tumor immune checkpoint blockade
(ICB) therapy in the past decade. Despite the considerable therapeutic effects, ICB is still …

Genome-editing-mediated restructuring of tumor immune microenvironment for prevention of metastasis

D Kim, Y Wu, G Shim, YK Oh - ACS nano, 2021 - ACS Publications
Modulating the tumor immune microenvironment to activate immune cells has been
investigated to convert cold to hot tumors. Here, we report that metal–lipid hybrid …

Indocyanine green-/TLR7 agonist-constructed thermosensitive liposome for low-temperature PTT induced synergistic immunotherapy of colorectal cancer

X Sun, Y Wang, T Du, Q Zhang, S Li, Q Chen… - Chinese Chemical …, 2023 - Elsevier
Colorectal cancer (CRC) is a lethal malignancy with a high mortality rate due to its low
immunogenicity, the strong immunosuppressive milieu and poor drug permeability. To …

[HTML][HTML] Monoclonal antibodies for chronic pain treatment: present and future

EM Sánchez-Robles, R Girón, N Paniagua… - International Journal of …, 2021 - mdpi.com
Chronic pain remains a major problem worldwide, despite the availability of various non-
pharmacological and pharmacological treatment options. Therefore, new analgesics with …

Reversing immune suppression and potentiating photothermal immunotherapy via bispecific immune checkpoint inhibitor loaded hollow polydopamine nanospheres

K Guo, D Chen, S Ren, MR Younis… - … Applied Materials & …, 2023 - ACS Publications
Despite the great achievements of immune checkpoint blockade (ICB) therapy on
programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) axis, ICB …

[HTML][HTML] Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and …

K Kaneko, CR Acharya, H Nagata, X Yang… - … for Immunotherapy of …, 2022 - ncbi.nlm.nih.gov
Background We previously demonstrated potent antitumor activity against human breast
cancer xenografts using photodynamic therapy (PDT) targeting a novel tumor-specific …

Smart nanocomposite assemblies for multimodal cancer theranostics

M Patel, A Prabhu - International Journal of Pharmaceutics, 2022 - Elsevier
Despite great strides in anticancer research, performance statistics of current treatment
modalities remain dismal, highlighting the need for safe, efficacious strategies for tumour …