Mitochondrial dysfunction in neurodegenerative diseases and drug targets via apoptotic signaling
Y Wu, M Chen, J Jiang - Mitochondrion, 2019 - Elsevier
Mitochondrial dysfunction is becoming one of the most emerging pathological process in the
etiology of neurological disorders. Other common etiologies of the neurological disorders …
etiology of neurological disorders. Other common etiologies of the neurological disorders …
[HTML][HTML] The role of mitochondria in amyotrophic lateral sclerosis
Mitochondria are unique organelles that are essential for a variety of cellular processes
including energy metabolism, calcium homeostasis, lipid biosynthesis, and apoptosis …
including energy metabolism, calcium homeostasis, lipid biosynthesis, and apoptosis …
Mitochondria‐targeted nanoparticles in treatment of neurodegenerative diseases
Y Zhang, H Yang, D Wei, X Zhang, J Wang, X Wu… - …, 2021 - Wiley Online Library
Neurodegenerative diseases (NDs) are a class of heterogeneous diseases that includes
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …
Alzheimer's disease, Parkinson's disease, Huntington's disease, and amyotrophic lateral …
The impact of mitochondrial dysfunction in amyotrophic lateral sclerosis
J Zhao, X Wang, Z Huo, Y Chen, J Liu, Z Zhao, F Meng… - Cells, 2022 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and highly fatal
neurodegenerative disease. Although the pathogenesis of ALS remains unclear, increasing …
neurodegenerative disease. Although the pathogenesis of ALS remains unclear, increasing …
Protective effects of apigenin on methylmercury-induced behavioral/neurochemical abnormalities and neurotoxicity in rats
Methylmercury (MeHg) is a neurotoxin that induces neurotoxicity and cell death in neurons.
MeHg increases oligodendrocyte death, glial cell activation, and motor neuron …
MeHg increases oligodendrocyte death, glial cell activation, and motor neuron …
[HTML][HTML] Linking mitochondrial dysfunction, metabolic syndrome and stress signaling in Neurodegeneration
SK Jha, NK Jha, D Kumar, RK Ambasta… - Biochimica et Biophysica …, 2017 - Elsevier
Mounting evidence suggests a link between metabolic syndrome (MetS) such as diabetes,
obesity, non-alcoholic fatty liver disease in the progression of Alzheimer's disease (AD) …
obesity, non-alcoholic fatty liver disease in the progression of Alzheimer's disease (AD) …
A robust TDP-43 knock-in mouse model of ALS
Amyotrophic lateral sclerosis (ALS) is a fatal, adult-onset degenerative disorder of motor
neurons. The diseased spinal cord motor neurons of more than 95% of amyotrophic lateral …
neurons. The diseased spinal cord motor neurons of more than 95% of amyotrophic lateral …
[HTML][HTML] Advances in nanotechnology-based strategies for the treatments of amyotrophic lateral sclerosis
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a
progressive neurodegenerative disease that affects both upper and lower motor neurons …
progressive neurodegenerative disease that affects both upper and lower motor neurons …
HIV-associated motor neuron disease: HERV-K activation and response to antiretroviral therapy
Objective: To determine whether there is activation of human endogenous retrovirus K
(HERV-K) in amyotrophic lateral sclerosis in HIV infection and whether it might respond to …
(HERV-K) in amyotrophic lateral sclerosis in HIV infection and whether it might respond to …
Among Gerontogens, heavy metals are a class of their own: A review of the evidence for cellular senescence
ST Vielee, JP Wise Jr - Brain Sciences, 2023 - mdpi.com
Advancements in modern medicine have improved the quality of life across the globe and
increased the average lifespan of our population by multiple decades. Current estimates …
increased the average lifespan of our population by multiple decades. Current estimates …