The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders

R Fetit, RF Hillary, DJ Price, SM Lawrie - Neuroscience & Biobehavioral …, 2021 - Elsevier
Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …

[HTML][HTML] Autism spectrum disorder: focus on glutamatergic neurotransmission

M Montanari, G Martella, P Bonsi… - International Journal of …, 2022 - mdpi.com
Disturbances in the glutamatergic system have been increasingly documented in several
neuropsychiatric disorders, including autism spectrum disorder (ASD). Glutamate-centered …

Virtual histology of cortical thickness and shared neurobiology in 6 psychiatric disorders

Y Patel, N Parker, J Shin, D Howard, L French… - JAMA …, 2021 - jamanetwork.com
Importance Large-scale neuroimaging studies have revealed group differences in cortical
thickness across many psychiatric disorders. The underlying neurobiology behind these …

Transcriptomic landscape and functional characterization of induced pluripotent stem cell–derived cerebral organoids in schizophrenia

A Kathuria, K Lopez-Lengowski, SS Jagtap… - JAMA …, 2020 - jamanetwork.com
Importance Three-dimensional cerebral organoids generated from patient-derived induced
pluripotent stem cells (iPSCs) may be used to interrogate cellular-molecular underpinnings …

Epitope-preserving magnified analysis of proteome (eMAP)

J Park, S Khan, DH Yun, T Ku, KL Villa, JE Lee… - Science …, 2021 - science.org
Synthetic tissue-hydrogel methods have enabled superresolution investigation of biological
systems using diffraction-limited microscopy. However, chemical modification by fixatives …

Glutamatergic neurotransmission: A potential pharmacotherapeutic target for the treatment of cognitive disorders

P Chakraborty, A Dey, AV Gopalakrishnan… - Ageing Research …, 2023 - Elsevier
In the mammalian brain, glutamate is regarded to be the primary excitatory neurotransmitter
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …

The evolution of the human brain and disease susceptibility

K Pattabiraman, SK Muchnik, N Sestan - Current opinion in genetics & …, 2020 - Elsevier
Evolutionary perspective is critical for understanding human biology, human medicine, and
the traits that make human beings unique. One of the crucial characteristics that sets …

[HTML][HTML] Zbtb16 regulates social cognitive behaviors and neocortical development

N Usui, S Berto, A Konishi, M Kondo, G Konopka… - Translational …, 2021 - nature.com
Zinc finger and BTB domain containing 16 (ZBTB16) play the roles in the neural progenitor
cell proliferation and neuronal differentiation during development, however, how the function …

The epilepsy–autism spectrum disorder phenotype in the era of molecular genetics and precision therapy

N Specchio, V Di Micco, M Trivisano, A Ferretti… - …, 2022 - Wiley Online Library
Autism spectrum disorder (ASD) is frequently associated with infants with epileptic
encephalopathy, and early interventions targeting social and cognitive deficits can have …

Dietary interventions, the gut microbiome, and aggressive behavior: Review of research evidence and potential next steps

M Tcherni‐Buzzeo - Aggressive behavior, 2023 - Wiley Online Library
Research in biosocial criminology and other related disciplines has established links
between nutrition and aggressive behavior. In addition to observational studies, randomized …