Abstract Three-dimensional (3D) human tissue models/microphysiological systems (eg,
organs-on-chips, organoids, and tissue explants) model HIV and related comorbidities and …

Genetically intact HIV-1 proviruses are a major concern with regard to curing infection
because they cause viral rebound after the cessation of antiretroviral therapy. However …

People with HIV are more likely to have opioid use disorder and to be prescribed opioids for
chronic pain than the general population; however, the effects of opioids on the immune …

People with HIV are more likely to have opioid use disorder and to be prescribed opioids for
chronic pain than the general population; however, the effects of opioids on the immune …

The combined effects of the HIV-1 and opioid epidemics on virus reservoir dynamics are
less well characterized. To assess the impact of opioid use on HIV-1 latency reversal, we …

The opioid epidemic may impact the HIV-1 reservoir and its reversal from latency in virally
suppressed people with HIV (PWH). We studied forty-seven PWH and observed that …

Antiretroviral therapy (ART) has dramatically prolonged the lives of people living with HIV
(PLWH), but it is not curative as it cannot eliminate integrated HIV-1 proviruses in different …

This paper is the forty-sixth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …