NIMH perspectives on future directions in neuroimaging for mental health

SA Wijtenburg, LM Rowland, A Vicentic… - …, 2024 - nature.com
NIMH's mission is to transform the understanding and treatment of mental illnesses through
basic and clinical research, paving the way for prevention, recovery, and cure. New imaging …

MRS-assessed brain GABA modulation in response to task performance and learning

H Li, G Rodríguez-Nieto, S Chalavi, C Seer… - Behavioral and Brain …, 2024 - Springer
Abstract Gamma-aminobutyric acid (GABA), the most important inhibitory neurotransmitter in
the human brain, has long been considered essential in human behavior in general and …

Universal dynamic fitting of magnetic resonance spectroscopy

WT Clarke, C Ligneul, M Cottaar, IB Ip… - Magnetic Resonance …, 2024 - Wiley Online Library
Abstract Purpose Dynamic (2D) MRS is a collection of techniques where acquisitions of
spectra are repeated under varying experimental or physiological conditions. Dynamic MRS …

Association between Inhibitory–Excitatory Balance and Brain Activity Response during Cognitive Flexibility in Young and Older Individuals

G Rodríguez-Nieto, DF Alvarez-Anacona… - Journal of …, 2024 - jneurosci.org
Cognitive flexibility represents the capacity to switch among different mental schemes,
providing an adaptive advantage to a changing environment. The neural underpinnings of …

[HTML][HTML] Glutamate dynamics and BOLD response during OCD symptom provocation in the lateral occipital cortex: A 7 Tesla fMRI-fMRS study

NT de Joode, OA van den Heuvel, M Koster… - Journal of Affective …, 2024 - Elsevier
Obsessive-compulsive disorder (OCD) is linked with dysfunction in frontal-striatal, fronto-
limbic, and visual brain regions. Research using proton magnetic resonance spectroscopy …

GABA, glutamatergic dynamics and BOLD contrast assessed concurrently using functional MRS during a cognitive task

AR Craven, G Dwyer, L Ersland… - NMR in …, 2024 - Wiley Online Library
A recurring issue in functional neuroimaging is how to link task‐driven haemodynamic blood
oxygen level dependent functional MRI (BOLD‐fMRI) responses to underlying …

Simultaneous multi‐transient linear‐combination modeling of MRS data improves uncertainty estimation

HJ Zöllner, C Davies‐Jenkins, D Simicic… - Magnetic resonance …, 2024 - Wiley Online Library
Purpose The interest in applying and modeling dynamic MRS has recently grown. Two‐
dimensional modeling yields advantages for the precision of metabolite estimation in …

Sequence building block for magnetic resonance spectroscopy on Siemens VE‐series scanners

J Karkouri, CT Rodgers - NMR in Biomedicine, 2024 - Wiley Online Library
We present a sequence building block (SBB) that embeds magnetic resonance
spectroscopy (MRS) into another sequence on the Siemens VE platform without any custom …

A 7T interleaved fMRS and fMRI study on visual contrast dependency in the human brain

A Schrantee, C Najac, C Jungerius… - Imaging …, 2023 - direct.mit.edu
Introduction: Functional magnetic resonance spectroscopy (fMRS) is a non-invasive
technique for measuring dynamic changes in neurometabolites. While previous studies …

Dynamics of γ-aminobutyric acid concentration in the human brain in response to short visual stimulation

A Yakovlev, A Gritskova, A Manzhurtsev… - … Resonance Materials in …, 2024 - Springer
Objective To find a possible quantitative relation between activation-induced fast (< 10 s)
changes in the γ-aminobutyric acid (GABA) level and the amplitude of a blood oxygen level …