Flavonoids in treatment of chronic kidney disease

YL Cao, JH Lin, HP Hammes, C Zhang - Molecules, 2022 - mdpi.com
Chronic kidney disease (CKD) is a progressive systemic disease, which changes the
function and structure of the kidneys irreversibly over months or years. The final common …

Plant Flavonoids with Antimicrobial Activity against Methicillin-Resistant Staphylococcus aureus (MRSA)

S Xu, A Kang, Y Tian, X Li, S Qin, R Yang… - ACS Infectious …, 2024 - ACS Publications
Methicillin-resistant Staphylococcus aureus (MRSA) has become a serious threat to human
public health and global economic development, and there is an urgent need to develop …

Hibifolin, a natural sortase a inhibitor, attenuates the pathogenicity of Staphylococcus aureus and enhances the antibacterial activity of cefotaxime

W Song, L Wang, Y Zhao, G Lanzi, X Wang… - Microbiology …, 2022 - Am Soc Microbiol
This study aimed to identify hibifolin as a sortase A (SrtA) inhibitor and to determine whether
it could attenuate the virulence of methicillin-resistant Staphylococcus aureus (MRSA). We …

Attenuating the virulence of the resistant superbug Staphylococcus aureus bacteria isolated from neonatal sepsis by ascorbic acid, dexamethasone, and sodium …

MM Saleh, N Yousef, SM Shafik, HA Abbas - BMC microbiology, 2022 - Springer
Background Infections affecting neonates caused by Staphylococcus aureus are
widespread in healthcare facilities; hence, novel strategies are needed to fight this …

Hinokiflavone attenuates the virulence of methicillin-resistant Staphylococcus aureus by targeting caseinolytic protease P

X Kong, B Wang, X Chen, L Wang… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Drug-resistant bacteria was the third leading cause of death worldwide in 2019, which
sounds like a cautionary note for global public health. Therefore, developing novel …

Ayanin, a natural flavonoid inhibitor of Caseinolytic protease, is a promising therapeutic agent to combat methicillin-resistant Staphylococcus aureus infections

M Jin, S Zhu, Y Tang, X Kong, X Wang, Y Li… - Biochemical …, 2023 - Elsevier
Antimicrobial resistance (AMR) is a global health threat. The dramatic increase of Methicillin-
resistant Staphylococcus aureus (MRSA) infections emphasizes the need to find new anti …

Thwarting resistance: MgrA inhibition with methylophiopogonanone a unveils a new battlefront against S. aureus

X Guo, L Wang, J Zhang, Q Liu, B Wang, D Liu… - npj Biofilms and …, 2024 - nature.com
Limitations in the clinical treatment of Staphylococcus aureus (S. aureus) infections have
arisen due to the advent of antibiotic-resistant strains. Given the immense potential of …

Tamarixetin Attenuated the Virulence of Staphylococcus aureus by Directly Targeting Caseinolytic Protease P

W Song, B Wang, L Sui, Y Shi, X Ren… - Journal of Natural …, 2022 - ACS Publications
Staphylococcus aureus, especially drug-resistant S. aureus infections, is a worldwide
healthcare challenge. There is a growing focus on antivirulence therapy against S. aureus …

Fish collagen peptides' modulating effect on human skin microbiota against pathogenic Staphylococcus aureus

R Bayan, I Tauseef, M Hussain, MS Ahmed… - Future …, 2023 - Future Medicine
Aim: The current research aims to design effective strategies to enhance the body's immune
system against pathogenic bacteria. Methods: Skin commensals were isolated, identified …

Exploring the potential of bis(thiazol-5-yl)phenylmethane derivatives as novel candidates against genetically defined multidrug-resistant Staphylococcus aureus

P Kavaliauskas, W Acevedo, A Garcia, E Naing… - Plos one, 2024 - journals.plos.org
Antimicrobial resistance (AMR) represents an alarming global challenge to public health.
Infections caused by multidrug-resistant Staphylococcus aureus (S. aureus) pose an …