Vasopressor therapy and blood pressure management in the setting of acute kidney injury

LW Busse, M Ostermann - Seminars in nephrology, 2019 - Elsevier
Acute kidney injury (AKI) is common in the setting of shock. Hemodynamic instability is a risk
factor for the development of AKI, and pathophysiological mechanisms include loss of renal …

[HTML][HTML] Controversies surrounding albumin use in Sepsis: lessons from Cirrhosis

CJ Wiedermann - International Journal of Molecular Sciences, 2023 - mdpi.com
This narrative review critically examines the role of albumin in sepsis management and
compares it to its well-established application in liver cirrhosis. Albumin, a key plasma …

[HTML][HTML] A novel risk-predicted nomogram for sepsis associated-acute kidney injury among critically ill patients

S Yang, T Su, L Huang, LH Feng, T Liao - BMC nephrology, 2021 - Springer
Background Acute kidney injury (AKI) is a prevalent and severe complication of sepsis
contributing to high morbidity and mortality among critically ill patients. In this retrospective …

[HTML][HTML] RAB10 overexpression promotes tumor growth and indicates poor prognosis of hepatocellular carcinoma

W Wang, WD Jia, B Hu, YY Pan - Oncotarget, 2017 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC), one of the most common and lethal cancers worldwide,
has a high recurrence rate with current treatment modalities. Identifying biomarkers for early …

LncRNA CAIF suppresses LPS‐induced inflammation and apoptosis of cardiomyocytes through regulating miR‐16 demethylation

Y Wang, Y Zhang - Immunity, Inflammation and Disease, 2021 - Wiley Online Library
Background The long noncoding RNA, cardiac autophagy inhibitory factor (CAIF), and
microRNA (miR)‐16 are reported to be involved in lipopolysaccharide (LPS)‐induced …

[HTML][HTML] The incidence, mortality and renal outcomes of acute kidney injury in patients with suspected infection at the emergency department

M Khairoun, JW Uffen, G Ocak, R Koopsen… - PLoS …, 2021 - journals.plos.org
Background Acute kidney injury (AKI) is a major health problem associated with
considerable mortality and morbidity. Studies on clinical outcomes and mortality of AKI in the …

IGFBP7 regulates sepsis‐induced acute kidney injury through ERK1/2 signaling

X Wang, T Ma, X Wan, Y Meng, Z Zhao… - Journal of cellular …, 2019 - Wiley Online Library
IGFBP7 as an early biomarker has been used to identify patients at risk of developing acute
kidney injury (AKI). Nevertheless, its role in AKI remains obscure. The aim of our study is to …

Oleanolic acid derivative isolated from Gardenia jasminoides var. radicans alleviates LPS-induced acute kidney injury in mice by reducing oxidative stress and …

M Zeng, Y Cao, R Xu, Y Wu, Y Wang, Y Zhang… - New Journal of …, 2020 - pubs.rsc.org
Acute kidney injury (AKI) is a frequent complication of sepsis with hallmarks including
inflammation and oxidative stress. A large amount of oleanolic acid derivatives (TO) have …

Long-term renal outcomes in adults with sepsis-induced acute kidney injury: a systematic review

PL Harris, RA Umberger - Dimensions of Critical Care Nursing, 2020 - journals.lww.com
Background Despite advances in medical technologies and intervention occurrences, acute
kidney injury (AKI) incidence continues to rise. Early interventions after sepsis are essential …

[HTML][HTML] MicroRNA-219 alleviates glutamate-induced neurotoxicity in cultured hippocampal neurons by targeting calmodulin-dependent protein kinase II gamma

T Wang, Q Cai, WJ Yang, HH Fan, JF Yi… - Neural regeneration …, 2018 - journals.lww.com
Septic encephalopathy is a frequent complication of sepsis, but there are few studies
examining the role of microRNAs (miRs) in its pathogenesis. In this study, a miR-219 mimic …