Chemical technologies for exploiting and recycling carbon dioxide into the value chain

M Peters, B Köhler, W Kuckshinrichs, W Leitner… - …, 2011 - Wiley Online Library
While experts in various fields discuss the potential of carbon capture and storage (CCS)
technologies, the utilization of carbon dioxide as chemical feedstock is also attracting …

Past, present and future of the Biginelli reaction: a critical perspective.

JS Sandhu - ARKIVOC: Online Journal of Organic …, 2012 - search.ebscohost.com
This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

Recent advances in asymmetric isocyanide‐based multicomponent reactions

SS van Berkel, BGM Bögels… - European Journal of …, 2012 - Wiley Online Library
Isocyanide‐based multicomponent reactions (IMCRs) can be considered one of the
breakthrough reaction classes of the last century. Moreover, asymmetric IMCRs have …

Synthesis and in vitro anticancer and antitubercular activity of diarylpyrazole ligated dihydropyrimidines possessing lipophilic carbamoyl group

RK Yadlapalli, OP Chourasia, K Vemuri… - Bioorganic & medicinal …, 2012 - Elsevier
A series of dihydropyrimidine derivatives were synthesized by utilizing Biginelli reaction and
evaluated for their in vitro anticancer activity against MCF-7 human breast cancer (HBC) cell …

Similarity and competition between Biginelli and Hantzsch reactions: An opportunity for modern medicinal chemistry

P Costanzo, M Nardi, M Oliverio - European Journal of Organic …, 2020 - Wiley Online Library
Similarity and competition between multicomponent reactions with similar mechanisms and
leading to similar scaffolds can be a useful tool for medicinal chemistry. In this review, we …

Synthesis and applications of 2-aminopyrimidine derivatives as key intermediates in chemical synthesis of biomolecules

EV Koroleva, KN Gusak… - Russian Chemical …, 2010 - iopscience.iop.org
Published data on the main approaches to the formation of the heterocyclic 2-
aminopyrimidine system, which is one of important pharmacophores responsible for the …

Biginelli and Hantzsch-type reactions leading to highly functionalized dihydropyrimidinone, thiocoumarin, and pyridopyrimidinone frameworks via ring annulation with …

GC Nandi, S Samai, MS Singh - The Journal of Organic Chemistry, 2010 - ACS Publications
An efficient and highly convergent route to dihydropyrimidinones (DHPMs) and hitherto
unreported dihydropyridopyrimidinones has been developed by one-pot, three-component …

Hantzsch-type dihydropyridines and biginelli-type tetra-hydropyrimidines: a review of their chemotherapeutic activities

S Sepehri, HP Sanchez… - Journal of Pharmacy & …, 2015 - journals.library.ualberta.ca
Years after the first report on 1, 4-dihydropyridines (1, 4-DHPs) and 1, 2, 3, 4-
tetrahydropyrimidines (1, 2, 3, 4-THPMs) appeared, they are revisited as plausible …

Post-Biginelli Ugi reaction towards synthesis of novel bisamides of dihydropyrimidinones: Substrate scope, modification and mechanism

RB Bhoraniya, M Koladiya, SR Desai, SG Modha - Tetrahedron, 2023 - Elsevier
A Biginelli, hydrolysis and Ugi four component reaction sequence was developed for the
synthesis of novel dihydropyrimidinone (DHPM) bisamides in which an unprecedented but …

Dotting the i's in three-component Biginelli-like condensations using 3-amino-1, 2, 4-triazole as a 1, 3-binucleophile

YV Sedash, NY Gorobets, VA Chebanov… - RSC …, 2012 - pubs.rsc.org
Alternative reaction pathways for Biginelli-like cyclocondensation reactions using 3-amino-1,
2, 4-triazole as a 1, 3-binucleophile under different reaction conditions lead to several types …